Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Glycomimetics for the inhibition and modulation of lectins

S Leusmann, P Ménová, E Shanin, A Titz… - Chemical Society …, 2023 - pubs.rsc.org
Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

M Li, H Zhou, C Yang, Y Wu, X Zhou, H Liu… - Journal of Controlled …, 2020 - Elsevier
Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …

Recent advances in subunit vaccine carriers

A Vartak, SJ Sucheck - Vaccines, 2016 - mdpi.com
The lower immunogenicity of synthetic subunit antigens, compared to live attenuated
vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that …

Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

S Wagner, R Sommer, S Hinsberger, C Lu… - Journal of medicinal …, 2016 - ACS Publications
Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …

Exploring multivalent carbohydrate–protein interactions by NMR

JI Quintana, U Atxabal, L Unione, A Ardá… - Chemical Society …, 2023 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) has been widely employed to assess diverse features
of glycan–protein molecular recognition events. Different types of qualitative and quantitative …

Carbohydrates in supramolecular chemistry

M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …

A biomimetic non‐antibiotic approach to eradicate drug‐resistant infections

Y Zhao, Q Guo, X Dai, X Wei, Y Yu, X Chen… - Advanced …, 2019 - Wiley Online Library
The chronic infections by pathogenic Pseudomonas aeruginosa (P. aeruginosa) remain to
be properly addressed. In particular, for drug‐resistant strains, limited medication is …

Glycosylated gold nanoparticles in point of care diagnostics: From aggregation to lateral flow

AN Baker, GW Hawker-Bond, PG Georgiou… - Chemical Society …, 2022 - pubs.rsc.org
Current point-of-care lateral flow immunoassays, such as the home pregnancy test, rely on
proteins as detection units (eg antibodies) to sense for analytes. Glycans play a fundamental …