Enzyme entrapment, biocatalyst immobilization without covalent attachment

HT Imam, PC Marr, AC Marr - Green Chemistry, 2021 - pubs.rsc.org
In entrapment an active species, which is often a catalyst, is trapped within a material by a
solid or gel forming event; thus, it becomes dispersed within the solid or semi-solid matrix …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …

J Qi, S Jia, X Kang, X Wu, Y Hong, K Shan… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …

Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials

X Du, J Zhou, J Shi, B Xu - Chemical reviews, 2015 - ACS Publications
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

Supramolecular biomaterials

MJ Webber, EA Appel, EW Meijer, R Langer - Nature materials, 2016 - nature.com
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

Drug self-delivery systems for cancer therapy

SY Qin, AQ Zhang, SX Cheng, L Rong, XZ Zhang - Biomaterials, 2017 - Elsevier
Carrier-assistant drug delivery systems (DDSs) have been rapidly established for cancer
therapy and great strides have been made in recent years. However, further development of …

Enzyme‐instructed self‐assembly (EISA) and hydrogelation of peptides

J Gao, J Zhan, Z Yang - Advanced materials, 2020 - Wiley Online Library
Self‐assembly is a powerful tool for constructing supramolecular materials for many
applications, ranging from energy harvesting to biomedicine. Among the methods to prepare …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Recent advances in subcellular targeted cancer therapy based on functional materials

WH Chen, GF Luo, XZ Zhang - Advanced Materials, 2019 - Wiley Online Library
Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

Peptide–drug conjugates as effective prodrug strategies for targeted delivery

Y Wang, AG Cheetham, G Angacian, H Su, L **e… - Advanced drug delivery …, 2017 - Elsevier
Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …