Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

AA Pollen, U Kilik, CB Lowe, JG Camp - Nature Reviews Genetics, 2023 - nature.com
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

Evolution of the human nervous system function, structure, and development

AMM Sousa, KA Meyer, G Santpere, FO Gulden… - Cell, 2017 - cell.com
The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …

A global catalog of whole-genome diversity from 233 primate species

LFK Kuderna, H Gao, MC Janiak, M Kuhlwilm, JD Orkin… - Science, 2023 - science.org
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …

The complete sequence and comparative analysis of ape sex chromosomes

KD Makova, BD Pickett, RS Harris, GA Hartley… - Nature, 2024 - nature.com
Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …

Phylogenomic analyses provide insights into primate evolution

Y Shao, L Zhou, F Li, L Zhao, BL Zhang, F Shao… - Science, 2023 - science.org
Comparative analysis of primate genomes within a phylogenetic context is essential for
understanding the evolution of human genetic architecture and primate diversity. We present …

A high-coverage Neandertal genome from Vindija Cave in Croatia

K Prüfer, C De Filippo, S Grote, F Mafessoni, P Korlević… - Science, 2017 - science.org
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

The Ensembl gene annotation system

BL Aken, S Ayling, D Barrell, L Clarke, V Curwen… - Database, 2016 - academic.oup.com
The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

A molecular view of kinetochore assembly and function

A Musacchio, A Desai - Biology, 2017 - mdpi.com
Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

Satellite DNA: an evolving topic

MA Garrido-Ramos - Genes, 2017 - mdpi.com
Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …

High-resolution comparative analysis of great ape genomes

ZN Kronenberg, IT Fiddes, D Gordon, S Murali… - Science, 2018 - science.org
INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …