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Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Evolution of the human nervous system function, structure, and development
The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …
most distinctive and impressive attributes. How the nervous system has changed in the …
A global catalog of whole-genome diversity from 233 primate species
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …
informative context in which to study the impact of genomic diversity on fundamental …
The complete sequence and comparative analysis of ape sex chromosomes
Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …
chromosome, which is present in both males and females. The Y chromosome is crucial for …
Phylogenomic analyses provide insights into primate evolution
Comparative analysis of primate genomes within a phylogenetic context is essential for
understanding the evolution of human genetic architecture and primate diversity. We present …
understanding the evolution of human genetic architecture and primate diversity. We present …
A high-coverage Neandertal genome from Vindija Cave in Croatia
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
The Ensembl gene annotation system
The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …
vertebrate species across a wide range of genome projects. Furthermore, it generates the …
A molecular view of kinetochore assembly and function
Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …
Satellite DNA: an evolving topic
MA Garrido-Ramos - Genes, 2017 - mdpi.com
Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …
High-resolution comparative analysis of great ape genomes
INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …
standing endeavor that requires the comprehensive discovery and comparison of all forms …