Immune function of endothelial cells: evolutionary aspects, molecular biology and role in atherogenesis

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Atherosclerosis is one of the key problems of modern medicine, which is due to the high
prevalence of atherosclerotic cardiovascular diseases and their significant share in the …

Engineering Vascular Bioreactor Systems to Closely Mimic Physiological Forces In Vitro

TC Mitchell, NL Feng, YT Lam, PL Michael… - … Engineering Part B …, 2023 - liebertpub.com
In vitro models of the vasculature play an important role in biomedical discovery research,
with diverse applications in vascular biology, drug discovery, and tissue engineering. These …

Participation of Krüppel-like factors in atherogenesis

S Kotlyarov, A Kotlyarova - Metabolites, 2023 - mdpi.com
Atherosclerosis is an important problem in modern medicine, the keys to understanding
many aspects of which are still not available to clinicians. Atherosclerosis develops as a …

Time-resolved simulation of blood flow through left anterior descending coronary artery: effect of varying extent of stenosis on hemodynamics

Y Zhao, H Wang, W Chen, W Sun, X Yu, C Sun… - BMC Cardiovascular …, 2023 - Springer
Background and objectives Real-time blood flow variation is crucial for understanding the
dynamic development of coronary atherosclerosis. The main objective of this study is to …

The impact of hemodynamic factors in a coronary main artery to detect the atherosclerotic severity: Single and multiple sequential stenosis cases

KE Hoque, M Ferdows, S Sawall, EE Tzirtzilakis… - Physics of …, 2021 - pubs.aip.org
A conventional invasive catheterization procedure is currently used to detect atherosclerotic
severity in coronary arteries. However, it is still challenging to measure multiple consecutive …

[HTML][HTML] Model of blood rheology including hemolysis based on population balance

J Krystian, M Łukasz, O Wojciech - Communications in Nonlinear Science …, 2023 - Elsevier
This study aimed to develop a universal rheological blood model that reflects physiological
processes related to blood in any blood vessel. Blood is a multicomponent fluid and its …

Sequentially suspended 3D bioprinting of multiple-layered vascular models with tunable geometries for in vitro modeling of arterial disorders initiation

C Pan, J Xu, Q Gao, W Li, T Sun, J Lu, Q Shi… - …, 2023 - iopscience.iop.org
As the main precursor of arterial disorders, endothelial dysfunction preferentially occurs in
regions of arteries prone to generating turbulent flow, particularly in branched regions of …

Hemolysis of red blood cells in blood vessels modeled via computational fluid dynamics

K Jędrzejczak, Ł Makowski, W Orciuch… - International Journal …, 2023 - Wiley Online Library
The research aims to verify the universal relationship between vessel shape and the risk of
hemolysis using a rheological model of blood reflecting the physiological processes related …

Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions

Q Li, S Yu, Y Wang, H Zhao, Z Gao, H Du, H Yang… - Trends in …, 2025 - cell.com
Replicating the contractile function of arterial tissues in vitro requires precise control of cell
alignment within 3D structures, a challenge that existing bioprinting techniques struggle to …

An open loop 0D-3D modeling of pulsatile hemodynamics for the diagnosis of a suspected coronary arterial disease with patient data

S Kumar, BV Kumar, SK Rai, O Shankar - Physics of Fluids, 2023 - pubs.aip.org
Due to the high degree of curvature of the coronary arteries, normal blood flow patterns are
disrupted, making them susceptible sites for stenosis and atherosclerosis, leading to …