Aspergillosis

BH Segal - New England Journal of Medicine, 2009 - Mass Medical Soc
This review discusses important advances in fungal diagnostics and in the antifungal
armamentarium as applied to aspergillus species. Recent insights concerning host defenses …

The changing face of epidemiology of invasive fungal disease in Europe

C Lass‐Flörl - Mycoses, 2009 - Wiley Online Library
Invasive fungal diseases (IFDs) are an increasingly common complication in critically ill
patients in Europe and are frequently fatal. Because of changes in treatment strategies and …

High-frequency Triazole Resistance Found In Nonculturable Aspergillus fumigatus from Lungs of Patients with Chronic Fungal Disease

DW Denning, S Park, C Lass-Florl… - Clinical infectious …, 2011 - academic.oup.com
Background. Oral triazole therapy is well established for the treatment of invasive (IPA),
allergic (ABPA), and chronic pulmonary (CPA) aspergillosis, and is often long-term. Triazole …

Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study

L Pagano, M Caira, A Candoni, M Offidani… - …, 2009 - pmc.ncbi.nlm.nih.gov
Background The aim of this study was to evaluate prognostic factors, treatments and
outcome of invasive aspergillosis in patients with acute myeloid leukemia based on data …

Aspergillus species identification in the clinical setting

SA Balajee, J Houbraken, PE Verweij… - Studies in …, 2007 - ingentaconnect.com
Multiple recent studies have demonstrated the limited utility of morphological methods used
singly for species identification of clinically relevant aspergilli. It is being increasingly …

Bronchoalveolar lavage fluid galactomannan for the diagnosis of invasive pulmonary aspergillosis in patients with hematologic diseases

J Maertens, V Maertens, K Theunissen… - Clinical infectious …, 2009 - academic.oup.com
Background. Prompt diagnosis of invasive pulmonary aspergillosis (IPA) remains a
challenge. Galactomannan (GM) detection in bronchoalveolar lavage (BAL) fluid by the …

Diagnosis and therapy of Candida infections: joint recommendations of the German Speaking Mycological Society and the Paul‐Ehrlich‐Society for Chemotherapy

M Ruhnke, V Rickerts, OA Cornely, D Buchheidt… - Mycoses, 2011 - Wiley Online Library
Invasive Candida infections are important causes of morbidity and mortality in
immunocompromised and hospitalised patients. This article provides the joint …

Prevalence of voriconazole-resistant invasive aspergillosis and its impact on mortality in haematology patients

A Resendiz-Sharpe, T Mercier… - Journal of …, 2019 - academic.oup.com
Abstract Background Increasing resistance of Aspergillus fumigatus to triazoles in high-risk
populations is a concern. Its impact on mortality is not well understood, but rates from 50% to …

The burden of Invasive Aspergillosis in patients with haematological malignancy: A meta-analysis and systematic review

RJ van de Peppel, LG Visser, OM Dekkers… - Journal of Infection, 2018 - Elsevier
Introduction Successful treatment of haematological malignancies is frequently complicated
by Invasive Aspergillosis (IA), a life-threatening fungal infection that occurs in at least 10% of …

High resolution computed tomography angiography improves the radiographic diagnosis of invasive mold disease in patients with hematological malignancies

M Stanzani, C Sassi, RE Lewis… - Clinical Infectious …, 2015 - academic.oup.com
Background. Computed tomography pulmonary angiography (CTPA) may improve the
diagnostic capabilities of CT imaging for invasive mold disease, but its performance relative …