Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Biological importance of imidazole nucleus in the new millennium

B Narasimhan, D Sharma, P Kumar - Medicinal Chemistry Research, 2011 - Springer
Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of
wide interest because of their diverse biological and clinical applications. This created …

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

D Sharma, B Narasimhan, P Kumar, V Judge… - European journal of …, 2009 - Elsevier
In the present study, we have synthesized 2-(substituted phenyl)-1H-imidazole (1–12) and
(substituted phenyl)-[2-(substituted phenyl)-imidazol-1-yl]-methanone (13–26) analogues …

Antibacterial, antifungal and in vitro antileukaemia activity of metal complexes with thiosemicarbazones

E Pahontu, F Julea, T Rosu, V Purcarea… - Journal of cellular …, 2015 - Wiley Online Library
phenyl‐3‐methyl‐4‐benzoyl‐5‐pyrazolone 4‐ethyl‐thiosemicarbazone (HL) and its copper
(II), vanadium (V) and nickel (II) complexes:[Cu (L)(Cl)]· C2H5OH·(1),[Cu (L) 2]· H2O (2),[Cu …

[HTML][HTML] Synthesis, characterization, antifungal, antibacterial and DNA cleavage studies of some heterocyclic Schiff base metal complexes

MS Nair, D Arish, RS Joseyphus - Journal of Saudi Chemical Society, 2012 - Elsevier
Co (II), Ni (II), Cu (II) and Zn (II) complexes of the Schiff base derived from indole-3-
carboxaldehyde and m-aminobenzoic acid were synthesized and characterized by …

Synthesis, structure elucidation, biological screening, molecular modeling and DNA binding of some Cu (II) chelates incorporating imines derived from amino acids

LH Abdel-Rahman, AM Abu-Dief, M Ismael… - Journal of Molecular …, 2016 - Elsevier
Three tridentate Schiff bases amino acids were prepared by direct condensation of 3-
methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with α-amino acid …

DNA, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium(ii) complexes of thiosemicarbazone ligands: effects of substitution on …

P Kalaivani, R Prabhakaran, F Dallemer… - Metallomics, 2012 - academic.oup.com
The coordination propensities of 4 (N, N′)-diethylaminosalicylaldehyde-4 (N)-substituted
thiosemicarbazones (H2L1–4) were investigated by reacting with an equimolar amount of …

Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu (I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA

A Chakraborty, SP Dash, AK Panda, R Acharyya… - Dalton …, 2015 - pubs.rsc.org
4-(pX-phenyl) thiosemicarbazone of napthaldehyde {where X= Cl (HL1) and X= Br (HL2)},
thiosemicarbazone of quinoline-2-carbaldehyde (HL3) and 4-(p-fluorophenyl) …

Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest

D Mahendiran, S Amuthakala, NSP Bhuvanesh… - RSC …, 2018 - pubs.rsc.org
A series of six new bis (thiosemicarbazone) copper (I) complexes of the type [Cu (L1–6)
2Cl](1–6) have been synthesized and characterized. The molecular structure of the ligand …

Synthesis, antimicrobial potential and computational studies of crystalline 4-bromo-2-(1, 4, 5-triphenyl-1 H-imidazole-2-yl) phenol and its metal complexes

AB Siddique, S Ahmad, MA Shaheen, A Ali, MN Tahir… - …, 2022 - pubs.rsc.org
Drug resistance developed in microorganisms is a major concern which needs immediate
attention from the scientific community. Development of new drugs with different modes of …