Pathophysiology of ST-segment elevation myocardial infarction: novel mechanisms and treatments

F Montecucco, F Carbone… - European heart …, 2016 - academic.oup.com
Despite major advances in mechanical and pharmacological reperfusion strategies to
improve acute myocardial infarction (MI) injury, substantial mortality, morbidity, and …

Ventricular remodeling after myocardial infarction: concepts and clinical implications

LAM Zornoff, SAR Paiva, DR Duarte… - Arquivos brasileiros de …, 2009 - SciELO Brasil
Background The word'remodeling'was used for the first time in association with myocardial
ischemia in 1982 by Hockman and Buckey while addressing the replacement of necrotic …

Sonothrombolysis in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

W Mathias, JM Tsutsui, BG Tavares, AM Fava… - Journal of the American …, 2019 - jacc.org
Background: Preclinical studies have demonstrated that high mechanical index (MI)
impulses from a diagnostic ultrasound transducer during an intravenous microbubble …

Diagnostic ultrasound impulses improve microvascular flow in patients with STEMI receiving intravenous microbubbles

W Mathias, JM Tsutsui, BG Tavares, F **e… - Journal of the American …, 2016 - jacc.org
Background: Pre-clinical trials have demonstrated that, during intravenous microbubble
infusion, high mechanical index (HMI) impulses from a diagnostic ultrasound (DUS) …

A review of therapeutic approaches for post-infarction left ventricular remodeling

A Matta, P Ohlmann, V Nader, N Moussallem… - Current Problems in …, 2024 - Elsevier
Left ventricular remodeling is an adaptive process initially developed in response to acute
myocardial infarction (AMI), but it ends up with negative adverse outcomes such as infarcted …

Prognostic value of microvascular resistance index immediately after primary percutaneous coronary intervention on left ventricular remodeling in patients with …

H Kitabata, T Kubo, K Ishibashi, K Komukai… - JACC: Cardiovascular …, 2013 - jacc.org
Objectives: This study sought to investigate the relationship between the degree of
microvascular dysfunction assessed by a dual-sensor guidewire (pressure and Doppler …

Stem‐cell therapy in ST‐segment elevation myocardial infarction with reduced ejection fraction: A multicenter, double‐blind randomized trial

JC Nicolau, RHM Furtado, SA Silva… - Clinical …, 2018 - Wiley Online Library
Background Left ventricular ejection fraction (LVEF) is a major determinant of long‐term
prognosis after ST‐segment elevation myocardial infarction (STEMI). STEMI patients with …

In patients with acute myocardial infarction, the impact of hyperglycemia as a risk factor for mortality is not homogeneous across age-groups

JC Nicolau, CV Serrano Jr, RR Giraldez… - Diabetes …, 2012 - diabetesjournals.org
OBJECTIVE To assess the impact of hyperglycemia in different age-groups of patients with
acute myocardial infarction (AMI). RESEARCH DESIGN AND METHODS A total of 2,027 …

Baseline glucose and left ventricular remodeling after acute myocardial infarction

JC Nicolau, LN Maia, JV Vitola, KW Mahaffey… - Journal of Diabetes and …, 2007 - Elsevier
In patients with acute myocardial infarction (AMI), the mechanisms behind the increased
mortality related to glucose levels (GL) are poorly understood. The main purpose of this …

[HTML][HTML] Severe impairment of left ventricular regional strain in STEMI patients is associated with post-infarct remodeling

GA Luisi, G Pestelli, G Lorenzoni, F Trevisan… - Journal of Clinical …, 2022 - mdpi.com
Background: Measures of global left ventricular (LV) systolic function have limitations for the
prediction of post-infarct LV remodeling (LVR). Therefore, we tested the association between …