[HTML][HTML] Microbiome and cancer
N Cullin, CA Antunes, R Straussman… - Cancer Cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …
interacts with the host across multiple body sites. Host-microbiome interactions impact …
The microbiome, cancer, and cancer therapy
BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …
tumor and host genomes as well as those of the vast array of microorganisms that exist …
Microbiota: a key orchestrator of cancer therapy
The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …
the epithelial barriers of the host. The commensal microbiota is important for the health and …
Gut microbiota modulation of chemotherapy efficacy and toxicity
Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
AK Nanayakkara, HW Boucher… - CA: a cancer journal …, 2021 - Wiley Online Library
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …
The role of the microbiome in cancer development and therapy
Answer questions and earn CME/CNE The human body harbors enormous numbers of
microbiota that influence cancer susceptibility, in part through their prodigious metabolic …
microbiota that influence cancer susceptibility, in part through their prodigious metabolic …
Role of the microbiota in response to and recovery from cancer therapy
Our understanding of how the microbiota affects the balance between response to and
failure of cancer treatment by modulating the tumour microenvironment and systemic …
failure of cancer treatment by modulating the tumour microenvironment and systemic …
Modulating the microbiome to improve therapeutic response in cancer
Although novel therapies, including immunotherapy, have dramatically improved outcomes
for many patients with cancer, overall outcomes are heterogeneous and existing biomarkers …
for many patients with cancer, overall outcomes are heterogeneous and existing biomarkers …
Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism
P Spanogiannopoulos, TS Kyaw, BGH Guthrie… - Nature …, 2022 - nature.com
Pharmaceuticals have extensive reciprocal interactions with the microbiome, but whether
bacterial drug sensitivity and metabolism is driven by pathways conserved in host cells …
bacterial drug sensitivity and metabolism is driven by pathways conserved in host cells …
[HTML][HTML] Gut microbiota modulation of efficacy and toxicity of cancer chemotherapy and immunotherapy
D Chrysostomou, LA Roberts, JR Marchesi, JM Kinross - Gastroenterology, 2023 - Elsevier
Accumulating evidence supports not only the functional role of the gut microbiome in cancer
development and progression but also its role in defining the efficacy and toxicity of …
development and progression but also its role in defining the efficacy and toxicity of …