A users guide to HPA axis research
Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …
Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators
Adolescence is a critical period for brain maturation. Deciphering how disturbances to the
central nervous system at this time affect structure, function and behavioural outputs is …
central nervous system at this time affect structure, function and behavioural outputs is …
Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats
A Ait-Belgnaoui, H Durand, C Cartier… - …, 2012 - Elsevier
BACKGROUND AND AIMS: Intestinal barrier impairment is incriminated in the
pathophysiology of intestinal gut disorders associated with psychiatric comorbidity …
pathophysiology of intestinal gut disorders associated with psychiatric comorbidity …
Probiotic gut effect prevents the chronic psychological stress‐induced brain activity abnormality in mice
Background A probiotic formulation (L actobacillus helveticus R0052 and B ifidobacterium
longum R0175 combination, Probio'Stick®) displays anxiolytic‐like activity and reduces …
longum R0175 combination, Probio'Stick®) displays anxiolytic‐like activity and reduces …
Microbiota modulate anxiety-like behavior and endocrine abnormalities in hypothalamic-pituitary-adrenal axis
R Huo, B Zeng, L Zeng, K Cheng, B Li, Y Luo… - Frontiers in Cellular …, 2017 - frontiersin.org
Intestinal microbes are an important system in the human body, with significant effects on
behavior. An increasing body of research indicates that intestinal microbes affect brain …
behavior. An increasing body of research indicates that intestinal microbes affect brain …
Neuroendocrine regulation of brain cytokines after psychological stress
There is growing evidence that stress-induced brain cytokines are important in the etiology
of depression and anxiety. Here, we review how the neuroendocrine responses to …
of depression and anxiety. Here, we review how the neuroendocrine responses to …
Cytokines in the brain and neuroinflammation: we didn't starve the fire!
JP Konsman - Pharmaceuticals, 2022 - mdpi.com
In spite of the brain-protecting tissues of the skull, meninges, and blood-brain barrier, some
forms of injury to or infection of the CNS can give rise to cerebral cytokine production and …
forms of injury to or infection of the CNS can give rise to cerebral cytokine production and …
Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages
ML Lehmann, HA Cooper, D Maric… - Journal of …, 2016 - Springer
Background We are interested in the causal interactions between psychological stress and
activity within different compartments of the immune system. Psychosocial stress has been …
activity within different compartments of the immune system. Psychosocial stress has been …
Novel aspects of glucocorticoid actions
Normal hypothalamic‐pituitary‐adrenal (HPA) axis activity leading to the rhythmic and
episodic release of adrenal glucocorticoids (GC s) is essential for body homeostasis and …
episodic release of adrenal glucocorticoids (GC s) is essential for body homeostasis and …
Repeated stress induces a pro-inflammatory state, increases amygdala neuronal and microglial activation, and causes anxiety in adult male rats
A link exists between immune function and psychiatric conditions, particularly depressive
and anxiety disorders. Psychological stress is a powerful trigger for these disorders and …
and anxiety disorders. Psychological stress is a powerful trigger for these disorders and …