While behavioral interventions remain the mainstay of treatment of autism spectrum disorder
(ASD), several potential targeted treatments addressing the underlying neurophysiology of …

Mental health challenges impede the well-being of autistic people. This Review outlines
contributing neurodevelopmental and physical health conditions, rates and developmental …

Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

We conducted systematic reviews and meta-analyses to evaluate the efficacy of melatonin
versus placebo or other hypnotic agents in improving sleep quality and quantity in patients …

Phelan–McDermid syndrome (PMS) is a genetic condition caused by SHANK3
haploinsufficiency and characterized by a wide range of neurodevelopmental and systemic …

There is a complex relationship between sleep disorders and childhood
neurodevelopmental, emotional, behavioral and intellectual disorders (NDEBID). NDEBID …

Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by distinctive
physical features, developmental delay, cognitive impairment, and a typical behavioral …

Daily rhythm of melatonin synchronizes the body to the light/dark environmental cycle.
Several hypotheses have been raised to understand the intersections between melatonin …

The prevalence of sleep dysfunction is considerably higher in the autistic population than in
the non-autistic. Similarly, the incidence of sensory reactivity differences in autism exceeds …

The manifestations of chronic insomnia undergo age-related changes. In younger infants
and children, behavioral insomnia emerges as the most prevalent form and typically …