Macrophages have important roles in immune surveillance and in the maintenance of
kidney homeostasis; their response to renal injury varies enormously depending on the …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Interstitial fibrosis is an important contributor to graft loss in chronic renal allograft injury.
Inflammatory macrophages are associated with fibrosis in renal allografts, but how these …

Macrophage-colony stimulating factor (CSF-1) signaling through its receptor (CSF-1R)
promotes the differentiation of myeloid progenitors into heterogeneous populations of …

Macrophages are found in normal kidney and in increased numbers in diseased kidney,
where they act as key players in renal injury, inflammation, and fibrosis. Macrophages are …

Certain macrophage phenotypes contribute to tissue fibrosis, but why? Tissues host resident
mononuclear phagocytes for their support to maintain homeostasis. Upon injury the …

Macrophages perform both injury-inducing and repair-promoting tasks in different models of
inflammation, leading to a model of macrophage function in which distinct patterns of …

Chronic kidney disease involves renal inflammation, interstitial fibrosis, and tubular and
vascular atrophy. Macrophages seem to foster all of these histomorphological abnormalities …

Renal dendritic cells (DCs) and macrophages represent a constitutive, extensive and
contiguous network of innate immune cells that provide sentinel and immune-intelligence …

Background. Although neutrophils and T cells are important in mediating renal injury
following ischaemia/reperfusion, the role of macrophages is still unknown. Using liposomal …