Metal nanoparticles as a promising technology in targeted cancer treatment

JJ Xu, WC Zhang, YW Guo, XY Chen, YN Zhang - Drug Delivery, 2022 - Taylor & Francis
Traditional anticancer treatments have several limitations, but cancer is still one of the
deadliest diseases. As a result, new anticancer drugs are required for the treatment of …

Carbon ion radiobiology

W Tinganelli, M Durante - Cancers, 2020 - mdpi.com
Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Review of the Geant4-DNA simulation toolkit for radiobiological applications at the cellular and DNA level

I Kyriakou, D Sakata, HN Tran, Y Perrot, WG Shin… - Cancers, 2021 - mdpi.com
Simple Summary A brief description of the methodologies to simulate ionizing radiation
transport in biologically relevant matter is presented. Emphasis is given to the physical …

[HTML][HTML] Gold nanoparticles as a potent radiosensitizer: A transdisciplinary approach from physics to patient

S Penninckx, AC Heuskin, C Michiels, S Lucas - Cancers, 2020 - mdpi.com
Over the last decade, a growing interest in the improvement of radiation therapies has led to
the development of gold-based nanomaterials as radiosensitizer. Although the …

[HTML][HTML] Recent developments in metallic nanomaterials for cancer therapy, diagnosing and imaging applications

DN Păduraru, D Ion, AG Niculescu, F Mușat… - Pharmaceutics, 2022 - mdpi.com
Cancer continues to represent a global health concern, imposing an ongoing need to
research for better treatment alternatives. In this context, nanomedicine seems to be the …

[HTML][HTML] A critical review of radiation therapy: from particle beam therapy (proton, carbon, and BNCT) to beyond

Y Matsumoto, N Fukumitsu, H Ishikawa… - Journal of personalized …, 2021 - mdpi.com
In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has
shown rapid progress and widespread use in recent years—in multidisciplinary treatment …

Prospects of nanoparticle-based radioenhancement for radiotherapy

LRH Gerken, ME Gerdes, M Pruschy… - Materials horizons, 2023 - pubs.rsc.org
Radiotherapy is a key pillar of solid cancer treatment. Despite a high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs at risk and subsequent …

Metal-based nanoparticle in cancer treatment: lessons learned and challenges

A Hheidari, J Mohammadi, M Ghodousi… - … in Bioengineering and …, 2024 - frontiersin.org
Cancer, being one of the deadliest diseases, poses significant challenges despite the
existence of traditional treatment approaches. This has led to a growing demand for …

Critical parameters to translate gold nanoparticles as radiosensitizing agents into the clinic

K Moloudi, A Khani, M Najafi… - Wiley …, 2023 - Wiley Online Library
Radiotherapy is an inevitable choice for cancer treatment that is applied as combinatorial
therapy along with surgery and chemotherapy. Nevertheless, radiotherapy at high doses …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …