Antibacterial and antioxidant activities for natural and synthetic dual-active compounds
G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …
century, since the past decades have seen a dramatic increase in human-pathogenic …
A review of the synthetic strategies toward spirobarbiturate-fused 3-to 7-membered rings
Spiro-connected hexahydropyrimidine-2, 4, 6-trione heterocyclic rings have received
increasing attention from the viewpoint of biological activity and synthetic methods due to the …
increasing attention from the viewpoint of biological activity and synthetic methods due to the …
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative …
J Figueiredo, JL Serrano, E Cavalheiro… - European journal of …, 2018 - Elsevier
Barbituric and thiobarbituric acid derivatives have become progressively attractive to
medicinal chemists due to their wide range of biological activities. Herein, different series of …
medicinal chemists due to their wide range of biological activities. Herein, different series of …
Electrochemical thiocyanation of barbituric acids
OV Bityukov, AS Kirillov, PY Serdyuchenko… - Organic & …, 2022 - pubs.rsc.org
The electrochemical thiocyanation of barbituric acids with NH4SCN was disclosed in an
undivided cell under constant current conditions. The electrosynthesis is the most efficient at …
undivided cell under constant current conditions. The electrosynthesis is the most efficient at …
Barbiturate- and Thiobarbituarte-Based s-Triazine Hydrazone Derivatives with Promising Antiproliferative Activities
A new class of compounds, which include s-triazine with pyrimidinetrione or
thiopyrimidinedione moiety through a hydrazone linkage, were synthesized and …
thiopyrimidinedione moiety through a hydrazone linkage, were synthesized and …
Hidden Reactivity of Barbituric and Meldrum's Acids: Atom-Efficient Free-Radical C–O Coupling with N-Hydroxy Compounds
IB Krylov, SA Paveliev, AS Budnikov, OO Segida… - …, 2021 - thieme-connect.com
The reactivity of CH-acidic and structurally related enol-containing heterocycles towards N-
oxyl radicals is disclosed. Traditionally, these substrates have been considered as reactants …
oxyl radicals is disclosed. Traditionally, these substrates have been considered as reactants …
Graphene Oxide Incorporated Strontium Nanoparticles as a Highly Efficient and Green Acid Catalyst for One-Pot Synthesis of Tetramethyl-9-aryl-hexahydroxanthenes and 13-Aryl-5H …
SR Mousavi, H Rashidi Nodeh, E Zamiri Afshari… - Catalysis Letters, 2019 - Springer
An efficient, inexpensive and recyclable graphene oxide/strontium nanocatalyst was
synthesized and applied in a pseudo three-component, one-pot cyclocondensation of …
synthesized and applied in a pseudo three-component, one-pot cyclocondensation of …
Visible light mediated, photocatalyst‐free condensation of barbituric acid with carbonyl compounds
An economical and efficient method has been developed for the production of dibarbiturates
of oxindole and arylidene barbituric acid derivatives via condensation of of isatin/aryl …
of oxindole and arylidene barbituric acid derivatives via condensation of of isatin/aryl …
Detailed theoretical characterization of azo chromophores containing dicyanomethylene acceptor and various coupling components by DFT
N Seferoğlu, G Toprakçıoğlu - Journal of Molecular Structure, 2019 - Elsevier
The structural, electronic and nonlinear optical (NLO) properties of a new series of donor-π-
acceptor (D-π-A) type azo dyes bearing strong electron-accepting dicyanomethylene unit …
acceptor (D-π-A) type azo dyes bearing strong electron-accepting dicyanomethylene unit …
Synthesis, structural characterization, and ADMET analysis of new pyrazol-pyrimidine derivatives
TM Mladenović, VM Matejić, SB Novaković… - Journal of Molecular …, 2025 - Elsevier
New pyrazol-pyrimidine derivatives were obtained starting from pyrazolone, barbituric acid,
and different substituted benzaldehydes, by reflux in a mixture of ethanol/water (1: 1) as a …
and different substituted benzaldehydes, by reflux in a mixture of ethanol/water (1: 1) as a …