[HTML][HTML] Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip

N Azizipour, R Avazpour, DH Rosenzweig, M Sawan… - Micromachines, 2020‏ - mdpi.com
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021‏ - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Microfluidics: innovations in materials and their fabrication and functionalization

JB Nielsen, RL Hanson, HM Almughamsi… - Analytical …, 2019‏ - ACS Publications
Microfluidics is a growing field of study because these devices offer novel and versatile
approaches for addressing a range of scientific problems. Microfluidics have been used in …

[HTML][HTML] Emerging trends in organ-on-a-chip systems for drug screening

Y Wang, Y Gao, Y Pan, D Zhou, Y Liu, Y Yin… - … Pharmaceutica Sinica B, 2023‏ - Elsevier
New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

[HTML][HTML] Organs-on-a-chip module: a review from the development and applications perspective

JE Sosa-Hernández, AM Villalba-Rodríguez… - Micromachines, 2018‏ - mdpi.com
In recent years, ever-increasing scientific knowledge and modern high-tech advancements
in micro-and nano-scales fabrication technologies have impacted significantly on various …

[HTML][HTML] Engineered liver-on-a-chip platform to mimic liver functions and its biomedical applications: A review

J Deng, W Wei, Z Chen, B Lin, W Zhao, Y Luo, X Zhang - Micromachines, 2019‏ - mdpi.com
Hepatology and drug development for liver diseases require in vitro liver models. Typical
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …

Advances in engineering human tissue models

CM Moysidou, C Barberio, RM Owens - Frontiers in bioengineering …, 2021‏ - frontiersin.org
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

[HTML][HTML] Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses

S Chen, Z Li, S Zhang, Y Zhou, X **ao, P Cui… - … Pharmaceutica Sinica B, 2022‏ - Elsevier
Pharmaceutical analysis is a discipline based on chemical, physical, biological, and
information technologies. At present, biotechnological analysis is a short branch in …

Voltage‐and Metal‐assisted Chemical Etching of Micro and Nano Structures in Silicon: A Comprehensive Review

S Surdo, G Barillaro - Small, 2024‏ - Wiley Online Library
Sculpting silicon at the micro and nano scales has been game‐changing to mold bulk silicon
properties and expand, in turn, applications of silicon beyond electronics, namely, in …

Organ-on-a-chip engineering: Toward bridging the gap between lab and industry

Q Ramadan, M Zourob - Biomicrofluidics, 2020‏ - pubs.aip.org
Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …