[HTML][HTML] Protein–protein interaction prediction with deep learning: A comprehensive review
Most proteins perform their biological function by interacting with themselves or other
molecules. Thus, one may obtain biological insights into protein functions, disease …
molecules. Thus, one may obtain biological insights into protein functions, disease …
Predicting protein–protein interactions from the molecular to the proteome level
Identification of protein–protein interactions (PPIs) is at the center of molecular biology
considering the unquestionable role of proteins in cells. Combinatorial interactions result in …
considering the unquestionable role of proteins in cells. Combinatorial interactions result in …
Multifaceted protein–protein interaction prediction based on Siamese residual RCNN
Motivation Sequence-based protein–protein interaction (PPI) prediction represents a
fundamental computational biology problem. To address this problem, extensive research …
fundamental computational biology problem. To address this problem, extensive research …
ProteinsPlus: a web portal for structure analysis of macromolecules
R Fährrolfes, S Bietz, F Flachsenberg… - Nucleic acids …, 2017 - academic.oup.com
With currently more than 126 000 publicly available structures and an increasing growth
rate, the Protein Data Bank constitutes a rich data source for structure-driven research in …
rate, the Protein Data Bank constitutes a rich data source for structure-driven research in …
Principles and overview of sampling methods for modeling macromolecular structure and dynamics
Investigation of macromolecular structure and dynamics is fundamental to understanding
how macromolecules carry out their functions in the cell. Significant advances have been …
how macromolecules carry out their functions in the cell. Significant advances have been …
Transient protein–protein interactions
Transient complexes are crucial for diverse biological processes such as biochemical
pathways and signaling cascades in the cell. Here, we give an overview of the transient …
pathways and signaling cascades in the cell. Here, we give an overview of the transient …
Protein–protein interaction and quaternary structure
Protein–protein recognition plays an essential role in structure and function. Specific non-
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
Structures of the extracellular regions of the group II/III metabotropic glutamate receptors
T Muto, D Tsuchiya, K Morikawa… - Proceedings of the …, 2007 - National Acad Sciences
Metabotropic glutamate receptors play major roles in the activation of excitatory synapses in
the central nerve system. We determined the crystal structure of the entire extracellular …
the central nerve system. We determined the crystal structure of the entire extracellular …
Human cancer protein-protein interaction network: a structural perspective
Protein-protein interaction networks provide a global picture of cellular function and
biological processes. Some proteins act as hub proteins, highly connected to others …
biological processes. Some proteins act as hub proteins, highly connected to others …
Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric states
K Hashimoto, AR Panchenko - Proceedings of the National …, 2010 - National Acad Sciences
The main principles of protein-protein recognition are elucidated by the studies of
homooligomers which in turn mediate and regulate gene expression, activity of enzymes …
homooligomers which in turn mediate and regulate gene expression, activity of enzymes …