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Stochastic models of intracellular transport
The interior of a living cell is a crowded, heterogenuous, fluctuating environment. Hence, a
major challenge in modeling intracellular transport is to analyze stochastic processes within …
major challenge in modeling intracellular transport is to analyze stochastic processes within …
From first-passage times of random walks in confinement to geometry-controlled kinetics
We present a general theory which allows one to accurately evaluate the mean first-passage
time (FPT) for regular random walks in bounded domains, and its extensions to related first …
time (FPT) for regular random walks in bounded domains, and its extensions to related first …
[ΒΙΒΛΙΟ][B] Stochastic processes in cell biology
PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …
components of a living cell operate in a highly noisy environment. What are the specific …
The narrow escape problem
D Holcman, Z Schuss - siam REVIEW, 2014 - SIAM
The narrow escape problem in diffusion theory is to calculate the mean first passage time of
a diffusion process to a small target on the reflecting boundary of a bounded domain. The …
a diffusion process to a small target on the reflecting boundary of a bounded domain. The …
An asymptotic analysis of the mean first passage time for narrow escape problems: Part II: The sphere
The mean first passage time (MFPT) is calculated for a Brownian particle in a spherical
domain in R^3 that contains N small nonoverlap** absorbing windows, or traps, on its …
domain in R^3 that contains N small nonoverlap** absorbing windows, or traps, on its …
Stochastic narrow escape in molecular and cellular biology
D Holcman, Z Schuss - Analysis and Applications. Springer, New York, 2015 - Springer
This monograph consists of two main parts, mathematical and biological. The mathematical
part, which is quite sophisticated involving advanced asymptotic methods in partial …
part, which is quite sophisticated involving advanced asymptotic methods in partial …
From single-particle stochastic kinetics to macroscopic reaction rates: fastest first-passage time of N random walkers
We consider the first-passage problem for N identical independent particles that are initially
released uniformly in a finite domain Ω and then diffuse toward a reactive area Γ, which can …
released uniformly in a finite domain Ω and then diffuse toward a reactive area Γ, which can …
Full distribution of first exit times in the narrow escape problem
In the scenario of the narrow escape problem (NEP) a particle diffuses in a finite container
and eventually leaves it through a small'escape window'in the otherwise impermeable …
and eventually leaves it through a small'escape window'in the otherwise impermeable …
Optimal reaction time for surface-mediated diffusion
We present an exact calculation of the mean first-passage time to a small target on the
surface of a 2D or 3D spherical domain, for a molecule performing surface-mediated …
surface of a 2D or 3D spherical domain, for a molecule performing surface-mediated …
First passage statistics for the capture of a Brownian particle by a structured spherical target with multiple surface traps
We study the first passage time problem for a diffusing molecule in an enclosed region to hit
a small spherical target whose surface contains many small absorbing traps. This study is …
a small spherical target whose surface contains many small absorbing traps. This study is …