Blood biomarkers have been considered tools for the diagnosis, prognosis, and monitoring
of Alzheimer's disease (AD). Although amyloid-β peptide (Aβ) and tau are primarily blood …

Alzheimer's disease (AD) is a complex disorder and the most common form of
neurodegenerative dementia. Several genetic, environmental, and physiological factors …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have …

We have demonstrated that the angiotensin-converting enzyme (ACE) genotype is
associated with Alzheimer's disease (AD) in the Japanese population (1). To determine why …

Alzheimer's disease (AD) is the most common type of dementia in the elderly population.
Three genes have been identified as responsible for the rare early-onset familial form of the …

We investigated the immunohistochemical alterations of angiotensin converting enzyme
(ACE), angiotensin II and AT1 receptor in the parietal cortex in Alzheimer's dementia (AD) to …

The renin‐angiotensin system (RAS) plays essential roles in maintaining peripheral
cardiovascular homeostasis, with its potential roles in the brain only being recognized more …

Abstract Apolipoprotein E ε4 (APOE* 4) is the only fully established susceptibility allele for
Alzheimer's disease. One of the most studied candidates is the insertion (I)/deletion (D) …

Polymorphisms of the renin–angiotensin system are associated with cardiovascular
disorders, possibly as a consequence of increased brain angiotensin II activity. Within the …

OBJECTIVES The Oxfordshire Community Stroke Project (OCSP) classification is a simple
clinical scheme for subdividing first ever acute stroke. Several small studies have shown that …