Mitochondrial membrane permeabilization in cell death
Irrespective of the morphological features of end-stage cell death (that may be apoptotic,
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …
[HTML][HTML] Cellular and molecular mechanisms of hepatic ischemia-reperfusion injury: The role of oxidative stress and therapeutic approaches
Ischemia-reperfusion (IR) or reoxygenation injury is the paradoxical exacerbation of cellular
impairment following restoration of blood flow after a period of ischemia during surgical …
impairment following restoration of blood flow after a period of ischemia during surgical …
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures
G Elaut, T Henkens, P Papeleu… - Current drug …, 2006 - ingentaconnect.com
Primary hepatocytes and their cultures are a simple but versatile, well-controlled, and
relatively easy to handle in vitro system that is well-accepted for investigating xenobiotic …
relatively easy to handle in vitro system that is well-accepted for investigating xenobiotic …
Prevention of contrast‐induced nephropathy through a knowledge of its pathogenesis and risk factors
Contrast‐induced nephropathy (CIN) is an iatrogenic acute renal failure (ARF) occurring
after the intravascular injection of iodinated radiographic contrast media. During the past …
after the intravascular injection of iodinated radiographic contrast media. During the past …
Low level light therapy for enhancement of neurologic function of a patient affected by Parkinson's disease
J Streeter, L De Taboada - US Patent 8,308,784, 2012 - Google Patents
1,856,969 A 5/1932 Reiter et a1. 3,735,755 A 5/1973 Eggleton et al. 3,810,367 A 5/1974
Peterson 4,076,393 A 2/1978 Bates 4,315,514 A 2/1982 Drewes et al. 4,343,301 A 8/1982 …
Peterson 4,076,393 A 2/1978 Bates 4,315,514 A 2/1982 Drewes et al. 4,343,301 A 8/1982 …
Trimetazidine: a review of its use in stable angina pectoris and other coronary conditions
KJ McClellan, GL Plosker - Drugs, 1999 - Springer
The orally administered antianginal agent trimetazidine increases cell tolerance to
ischaemia by maintaining cellular homeostasis. In theory, this cytoprotective activity should …
ischaemia by maintaining cellular homeostasis. In theory, this cytoprotective activity should …
Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia–reperfusion injury
L Argaud, L Gomez, O Gateau-Roesch… - Journal of molecular and …, 2005 - Elsevier
Trimetazidine (TMZ) affects mitochondrial function during ischemia. Mitochondrial
permeability transition is a pivotal event in cardiomyocyte death following acute ischemia …
permeability transition is a pivotal event in cardiomyocyte death following acute ischemia …
Mitochondrial membrane potential and ischemic neuronal death
T Iijima - Neuroscience research, 2006 - Elsevier
Mitochondria are intracellular organelles in which high energy phosphate is produced.
Ischemia causes depletion of the materials necessary to produce this phosphate and …
Ischemia causes depletion of the materials necessary to produce this phosphate and …
Mitochondria as target for antiischemic drugs
The cessation of blood flow followed by a reperfusion period results in severe damages to
cell structures. This induces a complex cascade of events involving, more particularly, a loss …
cell structures. This induces a complex cascade of events involving, more particularly, a loss …
Trimetazidine in the prevention of contrast-induced nephropathy after coronary procedures
Objective: To evaluate the efficacy of trimetazidine (TMZ) in the prevention of contrast-
induced nephropathy (CIN) in patients with high serum creatinine levels undergoing …
induced nephropathy (CIN) in patients with high serum creatinine levels undergoing …