The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
Exosome-based cell-cell communication in the tumor microenvironment
J Maia, S Caja, MC Strano Moraes, N Couto… - Frontiers in cell and …, 2018 - frontiersin.org
Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …
communication between transformed and non-transformed cells. The milieu created by …
The biology and function of exosomes in cancer
R Kalluri - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
Exosomes: new molecular targets of diseases
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and
they perform as key regulators in cell-to-cell communication in normal as well as diseased …
they perform as key regulators in cell-to-cell communication in normal as well as diseased …
Exosomes in cancer: small particle, big player
X Zhang, X Yuan, H Shi, L Wu, H Qian, W Xu - Journal of hematology & …, 2015 - Springer
Exosomes have emerged as a novel mode of intercellular communication. Exosomes can
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs …
Exosomes and tumor-mediated immune suppression
TL Whiteside - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Tumor-derived exosomes (TEX) are harbingers of tumor-induced immune suppression: they
carry immunosuppressive molecules and factors known to interfere with immune cell …
carry immunosuppressive molecules and factors known to interfere with immune cell …
Scalable production of extracellular vesicles and its therapeutic values: a review
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …
secreted by cells for intercellular communication. Recently, EVs have received much …
[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology
A Yokoi, T Ochiya - Seminars in cancer biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …