[HTML][HTML] Foundational statistical principles in medical research: sensitivity, specificity, positive predictive value, and negative predictive value

TF Monaghan, SN Rahman, CW Agudelo, AJ Wein… - Medicina, 2021 - mdpi.com
Sensitivity, which denotes the proportion of subjects correctly given a positive assignment
out of all subjects who are actually positive for the outcome, indicates how well a test can …

Biomarkers of sepsis: time for a reappraisal

C Pierrakos, D Velissaris, M Bisdorff, JC Marshall… - Critical Care, 2020 - Springer
Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …

Logistic regression in medical research

P Schober, TR Vetter - Anesthesia & Analgesia, 2021 - journals.lww.com
In this issue of Anesthesia & Analgesia, Park et al1 report results of an observational study
on the risk of hypoxemia (defined as a peripheral oxygen saturation< 90%) during rapid …

Statistics from A (agreement) to Z (z score): a guide to interpreting common measures of association, agreement, diagnostic accuracy, effect size, heterogeneity, and …

P Schober, EJ Mascha, TR Vetter - Anesthesia & Analgesia, 2021 - journals.lww.com
Researchers reporting results of statistical analyses, as well as readers of manuscripts
reporting original research, often seek guidance on how numeric results can be practically …

Statistical development and validation of clinical prediction models

SJ Staffa, D Zurakowski - Anesthesiology, 2021 - ingentaconnect.com
Clinical prediction models in anesthesia and surgery research have many clinical
applications including preoperative risk stratification with implications for clinical utility in …

Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury

SM Bossers, SA Loer, FW Bloemers… - Jama …, 2021 - jamanetwork.com
Importance The development and expansion of intracranial hematoma are associated with
adverse outcomes. Use of tranexamic acid might limit intracranial hematoma formation, but …

Prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in a middle-aged population with overweight and normal liver enzymes, and …

KC van Son, LC Te Nijenhuis-Noort, SC Boone… - Medicine, 2024 - journals.lww.com
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is
increasing at an alarming rate. Elevated liver enzymes are a primary reason to refer patients …

Sensitivity and complications of thoracentesis and thoracoscopy: a meta-analysis

G Martinez-Zayas, S Molina… - European Respiratory …, 2022 - publications.ersnet.org
Background Thoracentesis and thoracoscopy are used to diagnose malignant pleural
effusions (MPE). Data on how sensitivity varies with tumour type is limited. Methods …

Accuracy of online survey assessment of mental disorders and suicidal thoughts and behaviors in Spanish university students. Results of the WHO World Mental …

L Ballester, I Alayo, G Vilagut, J Almenara, AI Cebrià… - PloS one, 2019 - journals.plos.org
Objective To assess the accuracy of WMH-ICS online screening scales for evaluating four
common mental disorders (Major Depressive Episode [MDE], Mania/Hypomania [M/H] …

Diagnostic criteria of postoperative cognitive dysfunction: a focused systematic review

K van Sinderen, LA Schwarte… - … research and practice, 2020 - Wiley Online Library
Postoperative Cognitive Dysfunction (POCD) is characterized by a deterioration in cognitive
performance after surgery and is increasingly addressed in research studies. However, a …