Metabolic pathways reflect an organism's chemical repertoire and hence their elucidation
and design have been a primary goal in metabolic engineering. Various computational …

Plant flavonoids are secondary metabolites containing a benzo-γ-pyrone structure, which
are widely present in plants and have a variety of physiological and pharmacological …

Identifying functional enzymes for the catalysis of specific biochemical reactions is a major
bottleneck in the de novo design of biosynthesis and biodegradation pathways …

Thousands of biochemical reactions with characterized activities are “orphan,” meaning they
cannot be assigned to a specific enzyme, leaving gaps in metabolic pathways. Novel …

Fermentation products, together with food components, determine the sense, nutrition, and
safety of fermented foods. Traditional methods of fermentation product identification are time …

To increase the number of value-added chemicals that can be produced by metabolic
engineering and synthetic biology, constructing metabolic space with novel …

Glycosylation is a prominent strategy to optimize the pharmacokinetic and
pharmacodynamic properties of drug-like small-molecule scaffolds by modulating their …

Altered metabolism in cancer cells has been viewed as a passive response required for a
malignant transformation. However, this view has changed through the recently described …

Mycotoxins are likely to be converted into masked forms when subjected to plant metabolism
or food processing. These masked forms of mycotoxins together with their prototypes may …

Abstract Background Menaquinone-7 (MK-7), which is associated with complex and tightly
regulated pathways and redox imbalances, is produced at low titres in Bacillus subtilis …