RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …

Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …

The purpose of the work was to emphasize the main differences and similarities in the
degradation mechanisms in the case of polymeric coatings compared with the bulk ones …

One appealing concept in the field of hybrid materials is related to the design of gated
materials. These materials are prepared in such a way that the release of chemical or …

Organic nanoparticles with intriguing features have attracted widespread attention for
various biomedical applications, such as disease diagnosis, drug delivery, bioimaging, and …

Colorectal cancer (CRC) is one of the deadliest diseases worldwide due to a lack of early
detection methods and appropriate drug delivery strategies. Conventional imaging …

The extrinsic pathway is mediated by death receptors (DRs), including CD95 (APO-1/Fas) or
TRAILR-1/2. Defects in apoptosis regulation lead to cancer and other malignancies. The …

Nucleic acid‐based therapies are promising therapeutics for the treatment of several
systemic disorders, and they offer an exciting opportunity to address emerging biological …

Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have …