Potential involvement of the extracranial venous system in central nervous system disorders and aging

R Zivadinov, CP Chung - BMC medicine, 2013 - Springer
Background The role of the extracranial venous system in the pathology of central nervous
system (CNS) disorders and aging is largely unknown. It is acknowledged that the …

What went wrong? The flawed concept of cerebrospinal venous insufficiency

JM Valdueza, F Doepp, SJ Schreiber… - Journal of Cerebral …, 2013 - journals.sagepub.com
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the
central nervous system is associated with multiple sclerosis (MS), coining the term of chronic …

Brain venous haemodynamics, neurological diseases and mathematical modelling. A review

EF Toro - Applied Mathematics and Computation, 2016 - Elsevier
Abstract Behind Medicine (M) is Physiology (P), behind Physiology is Physics (P) and
behind Physics is always Mathematics (M), for which I expect that the symmetry of the …

Concomitant analysis of arterial, venous, and CSF flows using phase-contrast MRI: a quantitative comparison between MS patients and healthy controls

S ElSankari, O Balédent, V Van Pesch… - Journal of Cerebral …, 2013 - journals.sagepub.com
Venous dysfunction has recently been hypothesized to contribute to the pathophysiology of
multiple sclerosis (MS). 2D phase-contrast (PC) magnetic resonance imaging (MRI) is a non …

Patients with multiple sclerosis with structural venous abnormalities on MR imaging exhibit an abnormal flow distribution of the internal jugular veins

EM Haacke, W Feng, D Utriainen, G Trifan, Z Wu… - Journal of Vascular and …, 2012 - Elsevier
PURPOSE: To evaluate extracranial venous structural and flow characteristics in patients
with multiple sclerosis (MS). MATERIALS AND METHODS: Two hundred subjects with MS …

Venous drainage in multiple sclerosis: a combined MRI and ultrasound study

F Doepp, JT Würfel, CF Pfueller, JM Valdueza… - Neurology, 2011 - neurology.org
Background: Chronic cerebrospinal venous insufficiency (CCSVI) was proposed as the
causal trigger for develo** multiple sclerosis (MS). However, current data are …

Why current Doppler ultrasound methodology is inaccurate in assessing cerebral venous return: the alternative of the ultrasonic jugular venous pulse

P Zamboni - Behavioural Neurology, 2016 - Wiley Online Library
Assessment of cerebral venous return is growing interest for potential application in clinical
practice. Doppler ultrasound (DUS) was used as a screening tool. However, three meta …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives

R Zivadinov, M Ramanathan, K Dolic… - Expert review of …, 2011 - Taylor & Francis
Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in multiple
sclerosis patients. CCSVI is characterized by impaired brain venous drainage due to outflow …