Members of the Fos family (c-Fos, FosB and its smaller splice variants, Fra-1 and Fra-2)
dimerise with Jun proteins to form the AP-1 transcription factor complex. Based on the …

Both occupational and environmental exposure to particles is associated with an increased
risk of lung cancer. Particles are thought to impact on genotoxicity as well as on cell …

Bromodomain and extra terminal domain (BET) proteins function as epigenetic signaling
factors that associate with acetylated histones and facilitate transcription of target genes …

Reactive oxygen species (ROS) are constantly generated in aerobic organisms during
normal metabolism and in response to both internal and external stimuli. Imbalances in the …

In respiratory diseases, there is an increased expression of multiple inflammatory proteins in
the respiratory tract, including cytokines, chemokines, and adhesion molecules …

We recently used positional cloning to identify the transcription factor Nrf2 (NF‐E2 related
factor 2) as a susceptibility gene in a murine model of oxidant‐induced acute lung injury …

Classical Hodgkin lymphoma (cHL) and anaplastic lymphoma kinase-positive, anaplastic
large cell lymphoma (ALK+ ALCL) are B and T cell lymphomas respectively, which express …

Matrix stiffening is a prominent feature of pulmonary fibrosis. In this study, we demonstrate
that matrix stiffness regulates the ability of fibrotic lung myofibroblasts to invade the …

The article identifies the molecular and cell biology of healthy and diseased periodontal
tissues. The author provides components that influence the cellular activities of adjacent …

Exposure to asbestos causes cellular damage, leading to asbestosis, bronchogenic
carcinoma, and mesothelioma in humans. The pathogenesis of asbestos-related diseases is …