Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …

Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …

Conspectus Biomembranes are ubiquitous lipid structures that delimit the cell surface and
organelles and operate as platforms for a multitude of biomolecular processes. The …

Ferroptosis is a type of regulated necrosis caused by unrestricted lipid peroxidation and
subsequent plasma membrane rupture. However, the lipid remodeling mechanism that …

The ultimate microscope, directed at a cell, would reveal the dynamics of all the cell's
components with atomic resolution. In contrast to their real-world counterparts …

Bioactive peptides are key molecules in health and medicine. Deep learning holds a big
promise for the discovery and design of bioactive peptides. Yet, suitable experimental …

Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …

Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nano‐delivery system
for therapeutic nucleic acids. The great effort put in the development of ionizable lipids with …

Very-long-chain fatty acids (ie, fatty acids with more than 18 carbon atoms; VLCFA) are
important molecules that play crucial physiological and structural roles in plants. VLCFA are …

Lipids are essential constituents of cellular membranes. Once regarded merely as structural
components, lipids have taken centre stage with the discovery of their roles in cell signalling …