Tailored Metal-Based Catalysts: A New Platform for Targeted Anticancer Therapies

MIPS Leitão, TS Morais - Journal of Medicinal Chemistry, 2024‏ - ACS Publications
Innovative strategies for targeted anticancer therapies have gained significant momentum,
with metal complexes emerging as tunable catalysts for more effective and safer treatments …

Bioreactivity of divalent bimetallic vanadyl and zinc complexes bis-oxalyldihydrazone ligand against microbial and human cancer series. ctDNA interaction mode

MSS Adam, A Khalil - International Journal of Biological Macromolecules, 2023‏ - Elsevier
Two novel divalent bimetallic complexes were constructed from the complexation of O= V 4+
and Zn 2+ ions (VOL and ZnL), respectively, with diisatin oxalyldihydrazone ligand (H 2 L) …

Tailoring of some novel bis-hydrazone metal chelates, spectral based characterization and DFT calculations for pharmaceutical applications and in-silico treatments …

HA Qasem, MR Aouad, HA Al-Abdulkarim… - Journal of Molecular …, 2022‏ - Elsevier
A series of new bis-hydrazone complexes was obtained from ((N'E, N'''E)-2, 2′-(1, 3-
phenylenebis (oxy)) bis (N'-(4, 5-di-tert-butyl-2-hydroxybenzylidene) acetohydrazide)) ligand …

Comprehensive catalytic and biological studies on new designed oxo-and dioxo-metal (IV/VI) organic arylhydrazone frameworks

MJA Abualreish, ADM Mohamad, MSS Adam - Journal of Molecular Liquids, 2023‏ - Elsevier
Aryl Schiff base hydrazone have strong ability to form high stable complexes with transition
metals with numerous applicability in catalysis and biology. For that, mononuclear pincer …

Zn (II)-complexes of diisatin dihydrazones as effective catalysts in the oxidation protocol of benzyl alcohol and effective reagents for biological studies

MSS Adam - Journal of Molecular Liquids, 2023‏ - Elsevier
Two new dinuclear complexes of Zn 2+ ion (ZnLC2 and ZnLC6, respectively) with two novel
diisatin dihydrazone ligands of succinyl (H 2 LC2) and terephthalyl (H 2 LC2) derivatives …

Effect of Cu+/2+ ions on the biological activity of their bis‐oxalyldihydrazone complexes: ctDNA interaction, antimicrobial and anticancer action

MSS Adam, MA Mohamed - Applied Organometallic Chemistry, 2023‏ - Wiley Online Library
Two bimetallic homoleptic complexes (CuL1 and CuL2) were synthesized from the
coordination of Cu+/2+ ions with diisatin oxalyldihydrazone ligand (H2Lx), respectively …

Enhancing catalytic strategy for cyclic carbonates synthesized from CO2 and epoxides by using cobaloxime-based double complex salts as catalysts

A Alhafez, E Aytar, A Kilic - Journal of CO2 Utilization, 2022‏ - Elsevier
In this study, the novel neutral cobaloximes and corresponding to different cobaloxime-
based double complex salts were prepared and for the first time evaluated as an efficient …

Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review

I Czyżewska, L Mazur, Ł Popiołek - Chemical Biology & Drug …, 2024‏ - Wiley Online Library
Hydrazones display an interesting profile of biological activities, which includes mainly
antimicrobial and antiproliferative properties. Hydrazones also play an important role in the …

Design, preparation, physicochemical characterization, structural conformational, biological evaluation, and DNA interaction for some new benzimidazole complexes

AM Abu‐Dief, RM El‐Khatib, T El‐Dabea… - Applied …, 2024‏ - Wiley Online Library
New Cu (II), VO (II), Ag (I), and Pd (II)‐[BIP= 4, 6‐dimethyl‐N‐(octahydro‐2H‐benzimidazol‐
2‐ylidene) pyrimidin‐2‐amine] chelates have been synthesized by the reaction of BIP ligand …

[HTML][HTML] Designing of novel nano-sized coordination compounds based on Spinacia oleracea extract: Synthesis, structural characterization, molecular docking …

S Hosny, MR Shehata, SA Aly, AH Alsehli… - Inorganic Chemistry …, 2024‏ - Elsevier
A novel series of nano-sized metal chelates of 1-((E)-(2-mercaptophenylimino) methyl)
naphthalen-2-ol (H 2 L) Azo-methine ligand with Fe (III), Ni (II) and Ag (II) were prepared and …