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Multisystem physiological perspective of human frailty and its modulation by physical activity
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
Intermuscular adipose tissue in metabolic disease
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …
Resistance training for older adults: position statement from the national strength and conditioning association
Abstract Fragala, MS, Cadore, EL, Dorgo, S, Izquierdo, M, Kraemer, WJ, Peterson, MD, and
Ryan, ED. Resistance training for older adults: position statement from the national strength …
Ryan, ED. Resistance training for older adults: position statement from the national strength …
[HTML][HTML] An acetylation switch of the NLRP3 inflammasome regulates aging-associated chronic inflammation and insulin resistance
It is well documented that the rate of aging can be slowed, but it remains unclear to which
extent aging-associated conditions can be reversed. How the interface of immunity and …
extent aging-associated conditions can be reversed. How the interface of immunity and …
Inflammaging: The ground for sarcopenia?
Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …
elderly population, contributing to increased costs and hospitalization. Exercise and …
Hyperinsulinemia: an early indicator of metabolic dysfunction
DD Thomas, BE Corkey, NW Istfan… - Journal of the …, 2019 - academic.oup.com
Hyperinsulinemia is strongly associated with type 2 diabetes. Racial and ethnic minority
populations are disproportionately affected by diabetes and obesity-related complications …
populations are disproportionately affected by diabetes and obesity-related complications …
Heterogeneity of adipose tissue in development and metabolic function
T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …
compartmentalized into individual depots and distributed throughout the body. These …
Intermuscular fat: a review of the consequences and causes
O Addison, RL Marcus, PC LaStayo… - International journal of …, 2014 - Wiley Online Library
Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …
physical function in older adults. There is an increasing amount of research to support the …
Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction
NK Biltz, KH Collins, KC Shen… - The Journal of …, 2020 - Wiley Online Library
Key points Muscle infiltration with adipose tissue (IMAT) is common and associated with loss
of skeletal muscle strength and physical function across a diverse set of pathologies …
of skeletal muscle strength and physical function across a diverse set of pathologies …
Inflammatory markers in population studies of aging
T Singh, AB Newman - Ageing research reviews, 2011 - Elsevier
PURPOSE: To review findings from major epidemiologic studies regarding risk factors for
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …