Natural withanolides: an overview

LX Chen, H He, F Qiu - Natural product reports, 2011 - pubs.rsc.org
Covering: August 1996 to March 2010 Withanolides are a group of naturally occurring C28
steroids built on an ergostane skeleton functionalized at carbons 1, 22 and 26, commonly …

Natural withanolides, an update

G **a, S Cao, L Chen, F Qiu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …

Biological activity and structural diversity of steroids containing aromatic rings, phosphate groups, or halogen atoms

VM Dembitsky - Molecules, 2023 - mdpi.com
This review delves into the investigation of the biological activity and structural diversity of
steroids and related isoprenoid lipids. The study encompasses various natural compounds …

Withanolides and related steroids

RI Misico, VE Nicotra, JC Oberti, G Barboza… - Progress in the …, 2011 - Springer
Since the isolation of the first withanolides in the mid-1960s, over 600 new members of this
group of compounds have been described, with most from genera of the plant family …

Naturally occurring aromatic steroids and their biological activities

VM Dembitsky, N Savidov, VV Poroikov… - Applied microbiology …, 2018 - Springer
The present review describes the distribution and biological activities of natural mono-, di-,
and triaromatic steroids. It is shown that the producers of aromatic steroids are …

Cytotoxic Withanolide Constituents of Physalis longifolia

H Zhang, AK Samadi, RJ Gallagher… - Journal of Natural …, 2011 - ACS Publications
Fourteen new withanolides, 1–14, named withalongolides A–N, respectively, were isolated
from the aerial parts of Physalis longifolia together with eight known compounds (15–22) …

Antiproliferative activity of withanolides against human breast cancer cell lines

RP Machin, AS Veleiro, VE Nicotra… - Journal of natural …, 2010 - ACS Publications
The in vitro antiproliferative activity of a series of 22 naturally occurring withanolides was
examined against the T-47D, MCF7, MCF7/BUS, MDA-MB-231, and SK-Br-3 human solid …

Cytotoxicity of withanolides isolated from Acnistus arborescens

CP Cordero, SJ Morantes, A Páez, J Rincón… - Fitoterapia, 2009 - Elsevier
A new withanolide identified by spectroscopic analysis as 12β-acetoxy-4-deoxy-5, 6-deoxy-
Δ5–withanolide D and Withanolide D, were isolated from the leaves of Acnistus …

[HTML][HTML] Chemical Diversity of Ketosteroids as Potential Therapeutic Agents

VM Dembitsky - Microbiology Research, 2024 - mdpi.com
This article presents a comprehensive overview of recent discoveries and advancements in
the field of steroid chemistry, highlighting the isolation and characterization of various …

Capsisteroids A–F, withanolides from the leaves of Solanum capsicoides

BW Chen, YY Chen, YC Lin, CY Huang, C Uvarani… - RSC Advances, 2015 - pubs.rsc.org
A known withanolide steroid cilistol G (1) and six new withanolides, capsisteroids A–F (2–7),
were isolated from the EtOAc extract of the leaves of Solanum capsicoides. The structures of …