[HTML][HTML] AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation

M Entezari, D Hashemi, A Taheriazam… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is considered as a main challenge in both develo** and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …

[HTML][HTML] Therapeutic, and pharmacological prospects of nutmeg seed: A comprehensive review for novel drug potential insights

SS Al-Rawi, AH Ibrahim, HJ Ahmed… - Saudi Pharmaceutical …, 2024 - Elsevier
Background and objectives For centuries, plant seed extracts have been widely used and
valued for their benefits. They have been used in food, perfumes, aromatherapy, and …

[HTML][HTML] Plant-derived flavonoids as AMPK activators: unveiling their potential in type 2 diabetes management through mechanistic insights, docking studies, and …

DO Moon - Applied Sciences, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) remains a significant global health issue, marked by insulin
resistance and disrupted glucose metabolism. AMP-activated protein kinase (AMPK) serves …

Nutmegs and wild nutmegs: An update on ethnomedicines, phytochemicals, pharmacology, and toxicity of the Myristicaceae species

R Barman, PK Bora, J Saikia, P Kemprai… - Phytotherapy …, 2021 - Wiley Online Library
Prized medicinal spice true nutmeg is obtained from Myristica fragrans Houtt. Rest species
of the family Myristicaceae are known as wild nutmegs. Nutmegs and wild nutmegs are a …

[HTML][HTML] Sexual Dimorphism in Cardiometabolic Diseases: The Role of AMPK

M Kvandova, A Puzserova, P Balis - International Journal of Molecular …, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of mortality and disability among
both males and females. The risk of cardiovascular diseases is heightened by the presence …

Acylphenols and Dimeric Acylphenols from the Genus Myristica: A Review of Their Phytochemistry and Pharmacology

MA Othman, Y Sivasothy - Plants, 2023 - mdpi.com
The genus Myristica is a medicinally important genus belonging to the Myristicaceae.
Traditional medicinal systems in Asia have employed plants from the genus Myristica to treat …

Phenylpropanoids and neolignans isolated from Myristica fragrans enhance glucose uptake in myotubes

Y Yoshioka, R Kono, M Kuse, Y Yamashita… - Food & Function, 2022 - pubs.rsc.org
Nutmeg is the seed of Myristica fragrans or its powder and is used as a spice and a
traditional medicine. The antidiabetic effect of nutmeg is not fully understood yet. In this …

The effect of curcumin on PI3K/Akt and AMPK pathways in insulin resistance induced by fructose

G Kiren, Ç Severcan, SM Severcan… - Turkish Journal of …, 2024 - degruyter.com
Objectives Excessive fructose consumption is recognized to elevate insulin resistance in
animals and humans. In our study, we aimed to assess the possible consequences of …

Assessment of the antidiabetic potentiality of glyburide loaded glyceryl monostearate solid lipid nanoparticles

S Mukherjee, S Maity, B Ghosh, T Chakraborty… - Journal of Drug Delivery …, 2020 - Elsevier
The high rate homogenisation techniques was used for preparing glyburide loaded glyceryl
monostearate solid lipid nanoparticles (Glb-SLNs) to improve the drug's solubility and oral …

Bioactivity potential and chemical profile of endophytic Stutzerimonas stutzeri strain D2 isolated from Myristica fatua Houtt.

JA Priyanto, G Primahana, ME Prastya… - Journal of Research …, 2024 - search.ebscohost.com
Endophytic bacteria isolated from medicinal plants are recognized as a source of valuable
secondary metabolites. The present study aimed to isolate and evaluate the potential …