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[HTML][HTML] AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation
Diabetes mellitus (DM) is considered as a main challenge in both develo** and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …
developed countries, as lifestyle has changed and its management seems to be vital. Type I …
[HTML][HTML] Therapeutic, and pharmacological prospects of nutmeg seed: A comprehensive review for novel drug potential insights
Background and objectives For centuries, plant seed extracts have been widely used and
valued for their benefits. They have been used in food, perfumes, aromatherapy, and …
valued for their benefits. They have been used in food, perfumes, aromatherapy, and …
[HTML][HTML] Plant-derived flavonoids as AMPK activators: unveiling their potential in type 2 diabetes management through mechanistic insights, docking studies, and …
DO Moon - Applied Sciences, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) remains a significant global health issue, marked by insulin
resistance and disrupted glucose metabolism. AMP-activated protein kinase (AMPK) serves …
resistance and disrupted glucose metabolism. AMP-activated protein kinase (AMPK) serves …
Nutmegs and wild nutmegs: An update on ethnomedicines, phytochemicals, pharmacology, and toxicity of the Myristicaceae species
Prized medicinal spice true nutmeg is obtained from Myristica fragrans Houtt. Rest species
of the family Myristicaceae are known as wild nutmegs. Nutmegs and wild nutmegs are a …
of the family Myristicaceae are known as wild nutmegs. Nutmegs and wild nutmegs are a …
[HTML][HTML] Sexual Dimorphism in Cardiometabolic Diseases: The Role of AMPK
M Kvandova, A Puzserova, P Balis - International Journal of Molecular …, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of mortality and disability among
both males and females. The risk of cardiovascular diseases is heightened by the presence …
both males and females. The risk of cardiovascular diseases is heightened by the presence …
Acylphenols and Dimeric Acylphenols from the Genus Myristica: A Review of Their Phytochemistry and Pharmacology
MA Othman, Y Sivasothy - Plants, 2023 - mdpi.com
The genus Myristica is a medicinally important genus belonging to the Myristicaceae.
Traditional medicinal systems in Asia have employed plants from the genus Myristica to treat …
Traditional medicinal systems in Asia have employed plants from the genus Myristica to treat …
Phenylpropanoids and neolignans isolated from Myristica fragrans enhance glucose uptake in myotubes
Nutmeg is the seed of Myristica fragrans or its powder and is used as a spice and a
traditional medicine. The antidiabetic effect of nutmeg is not fully understood yet. In this …
traditional medicine. The antidiabetic effect of nutmeg is not fully understood yet. In this …
The effect of curcumin on PI3K/Akt and AMPK pathways in insulin resistance induced by fructose
G Kiren, Ç Severcan, SM Severcan… - Turkish Journal of …, 2024 - degruyter.com
Objectives Excessive fructose consumption is recognized to elevate insulin resistance in
animals and humans. In our study, we aimed to assess the possible consequences of …
animals and humans. In our study, we aimed to assess the possible consequences of …
Assessment of the antidiabetic potentiality of glyburide loaded glyceryl monostearate solid lipid nanoparticles
The high rate homogenisation techniques was used for preparing glyburide loaded glyceryl
monostearate solid lipid nanoparticles (Glb-SLNs) to improve the drug's solubility and oral …
monostearate solid lipid nanoparticles (Glb-SLNs) to improve the drug's solubility and oral …
Bioactivity potential and chemical profile of endophytic Stutzerimonas stutzeri strain D2 isolated from Myristica fatua Houtt.
Endophytic bacteria isolated from medicinal plants are recognized as a source of valuable
secondary metabolites. The present study aimed to isolate and evaluate the potential …
secondary metabolites. The present study aimed to isolate and evaluate the potential …