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Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release
A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
delivery method of drugs that are poorly soluble in water. The investigations carried out have …
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) prepared by microwave and ultrasound-assisted synthesis: promising green strategies for the …
Many pharmaceutically active molecules are highly lipophilic, which renders their
administration and adsorption in patients extremely challenging. Among the countless …
administration and adsorption in patients extremely challenging. Among the countless …
Influence of the drug distribution in electrospun gliadin fibers on drug-release behavior
Y Xu, JJ Li, DG Yu, GR Williams, JH Yang… - European Journal of …, 2017 - Elsevier
Drug distribution within its carrier in a solid dosage form often generates a profound
influence on its release profile, particularly when the physicochemical properties of the …
influence on its release profile, particularly when the physicochemical properties of the …
pH-sensitive Eudragit® L 100 nanoparticles promote cutaneous penetration and drug release on the skin
Nanoparticles (NPs) are promising carriers for dermal and transdermal drug delivery.
However, the underlying dynamics of drug release from the NPs, especially, how the …
However, the underlying dynamics of drug release from the NPs, especially, how the …
An insight of techniques for the assessment of permeation flux across the skin for optimization of topical and transdermal drug delivery systems
The skin has been employed as a delivery route for localized as well as systemic delivery of
drugs. However, the Stratum corneum (SC) of the skin act as a main barrier for the …
drugs. However, the Stratum corneum (SC) of the skin act as a main barrier for the …
Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels
M Giulbudagian, S Hönzke, J Bergueiro, D Işık… - Nanoscale, 2018 - pubs.rsc.org
Highly hydrophilic, responsive nanogels are attractive as potential systems for the topical
delivery of bioactives encapsulated in their three-dimensional polymeric scaffold. Yet, these …
delivery of bioactives encapsulated in their three-dimensional polymeric scaffold. Yet, these …
[HTML][HTML] Nanocrystals for improved drug delivery of dexamethasone in skin investigated by EPR spectroscopy
Nanocrystals represent an improvement over the traditional nanocarriers for dermal
application, providing the advantages of 100% drug loading, a large surface area, increased …
application, providing the advantages of 100% drug loading, a large surface area, increased …
Improved tacrolimus skin permeation by co-encapsulation with clobetasol in lipid nanoparticles: Study of drug effects in lipid matrix by electron paramagnetic …
LM Andrade, LAD Silva, AP Krawczyk-Santos… - European journal of …, 2017 - Elsevier
Combined therapy with corticosteroids and immunosuppressant-loaded nanostructured lipid
carriers (NLC) could be useful in the treatment of skin diseases. To circumvent NLC loading …
carriers (NLC) could be useful in the treatment of skin diseases. To circumvent NLC loading …
[HTML][HTML] Biomolecular EPR meets NMR at high magnetic fields
In this review on advanced biomolecular EPR spectroscopy, which addresses both the EPR
and NMR communities, considerable emphasis is put on delineating the complementarity of …
and NMR communities, considerable emphasis is put on delineating the complementarity of …
[HTML][HTML] Control of API release with matrix polymorphism in tristearin microspheres
AM Pluntze, JL Cape, ND Klaus, DK Lyon - International Journal of …, 2023 - Elsevier
Glycerides are widely employed as solid matrices in a range of pharmaceutical
intermediates and dosage forms. Diffusion-based mechanisms are responsible for drug …
intermediates and dosage forms. Diffusion-based mechanisms are responsible for drug …