Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) prepared by microwave and ultrasound-assisted synthesis: promising green strategies for the …

KL López, A Ravasio, JV González-Aramundiz… - Pharmaceutics, 2023 - mdpi.com
Many pharmaceutically active molecules are highly lipophilic, which renders their
administration and adsorption in patients extremely challenging. Among the countless …

Influence of the drug distribution in electrospun gliadin fibers on drug-release behavior

Y Xu, JJ Li, DG Yu, GR Williams, JH Yang… - European Journal of …, 2017 - Elsevier
Drug distribution within its carrier in a solid dosage form often generates a profound
influence on its release profile, particularly when the physicochemical properties of the …

pH-sensitive Eudragit® L 100 nanoparticles promote cutaneous penetration and drug release on the skin

P Dong, FF Sahle, SB Lohan, S Saeidpour… - Journal of Controlled …, 2019 - Elsevier
Nanoparticles (NPs) are promising carriers for dermal and transdermal drug delivery.
However, the underlying dynamics of drug release from the NPs, especially, how the …

An insight of techniques for the assessment of permeation flux across the skin for optimization of topical and transdermal drug delivery systems

S Chaturvedi, A Garg - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
The skin has been employed as a delivery route for localized as well as systemic delivery of
drugs. However, the Stratum corneum (SC) of the skin act as a main barrier for the …

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels

M Giulbudagian, S Hönzke, J Bergueiro, D Işık… - Nanoscale, 2018 - pubs.rsc.org
Highly hydrophilic, responsive nanogels are attractive as potential systems for the topical
delivery of bioactives encapsulated in their three-dimensional polymeric scaffold. Yet, these …

[HTML][HTML] Nanocrystals for improved drug delivery of dexamethasone in skin investigated by EPR spectroscopy

SB Lohan, S Saeidpour, M Colombo, S Staufenbiel… - Pharmaceutics, 2020 - mdpi.com
Nanocrystals represent an improvement over the traditional nanocarriers for dermal
application, providing the advantages of 100% drug loading, a large surface area, increased …

Improved tacrolimus skin permeation by co-encapsulation with clobetasol in lipid nanoparticles: Study of drug effects in lipid matrix by electron paramagnetic …

LM Andrade, LAD Silva, AP Krawczyk-Santos… - European journal of …, 2017 - Elsevier
Combined therapy with corticosteroids and immunosuppressant-loaded nanostructured lipid
carriers (NLC) could be useful in the treatment of skin diseases. To circumvent NLC loading …

[HTML][HTML] Biomolecular EPR meets NMR at high magnetic fields

K Möbius, W Lubitz, N Cox, A Savitsky - Magnetochemistry, 2018 - mdpi.com
In this review on advanced biomolecular EPR spectroscopy, which addresses both the EPR
and NMR communities, considerable emphasis is put on delineating the complementarity of …

[HTML][HTML] Control of API release with matrix polymorphism in tristearin microspheres

AM Pluntze, JL Cape, ND Klaus, DK Lyon - International Journal of …, 2023 - Elsevier
Glycerides are widely employed as solid matrices in a range of pharmaceutical
intermediates and dosage forms. Diffusion-based mechanisms are responsible for drug …