Stereoselective Remote Functionalization via Palladium‐Catalyzed Redox‐Relay Heck Methodologies
Exploration of novel, three‐dimensional chemical space is of growing interest in the drug
discovery community and with this comes the challenge for synthetic chemists to devise new …
discovery community and with this comes the challenge for synthetic chemists to devise new …
Optimizing the Heck–Matsuda reaction in flow with a constraint-adapted direct search algorithm
The optimization of a palladium-catalyzed Heck–Matsuda reaction using an optimization
algorithm is presented. We modified and implemented the Nelder–Mead method in order to …
algorithm is presented. We modified and implemented the Nelder–Mead method in order to …
Antimicrobial activities of two 1‐D, 2‐D, and 3‐D mononuclear Mn (II) and dinuclear Bi (III) complexes: X‐ray structures, spectroscopic, electrostatic potential, Hirshfeld …
YM Chai, CG Li, XF Zhang… - Applied Organometallic …, 2022 - Wiley Online Library
Two mononuclear and dinuclear octahedral complexes,[Mn (L1) 2Cl2](1) and [Bi2 (L2)
2Cl8](2)(L1= 2‐(2‐pyridyl)‐4‐methyl‐1, 2‐dihydroquinazoline‐N3‐oxide, L2= 2‐(3‐pyridyl) …
2Cl8](2)(L1= 2‐(2‐pyridyl)‐4‐methyl‐1, 2‐dihydroquinazoline‐N3‐oxide, L2= 2‐(3‐pyridyl) …
Enantioselective, Noncovalent, Substrate‐Directable Heck–Matsuda and Oxidative Heck Arylations of Unactivated Five‐Membered Carbocyclic Olefins
JM de Oliveira, RA Angnes, IU Khan… - … A European Journal, 2018 - Wiley Online Library
Highly diastereo‐and enantioselective, noncovalent, substrate‐directable Heck
desymmetrizations of cyclopentenyl olefins containing hydroxymethyl and carboxylate …
desymmetrizations of cyclopentenyl olefins containing hydroxymethyl and carboxylate …
Pd-Catalyzed Decarboxylation and Dual C(sp3)–H Functionalization Protocols for the Synthesis of 2,4-Diarylpyridines
The Pd-catalyzed decarboxylation and dual C (sp3)–H bond functionalization approaches
have been described for the preparation of symmetrical and unsymmetrical 2, 4 …
have been described for the preparation of symmetrical and unsymmetrical 2, 4 …
Steric evaluation of Pyox ligands for asymmetric intermolecular Heck-Matsuda reaction
A structure selectivity relationship was established by systematically increasing the steric of
the ligands from phenyl substituent to mesityl on the pyridine ring of Pyox and isopropyl to …
the ligands from phenyl substituent to mesityl on the pyridine ring of Pyox and isopropyl to …
Synthesis of Arylidene-β-lactams via exo-Selective Matsuda-Heck Arylation of Methylene-β-lactams
N Riemer, M Riemer, M Krüger… - The Journal of …, 2021 - ACS Publications
exo-Methylene-β-lactams were synthesized in two steps from commercially available 3-
bromo-2-(bromomethyl) propionic acid and reacted with arene diazonium salts in a Heck …
bromo-2-(bromomethyl) propionic acid and reacted with arene diazonium salts in a Heck …
Enantioselective heck arylation of acyclic alkenol aryl ethers: synthetic applications and DFT investigation of the stereoselectivity
EC Polo, MF Wang, RA Angnes… - Advanced Synthesis …, 2020 - Wiley Online Library
Herein we report the enantioselective Heck‐Matsuda arylation of acyclic E and Z‐alkenyl
aryl ethers. The reactions were carried out under mild conditions affording the …
aryl ethers. The reactions were carried out under mild conditions affording the …
Anwendung von Organometallkatalysatoren in der API-Synthese
Die inhärente Kreativität von synthetischen organischen Chemikern ist halluzinogen und hat
das Potenzial, die globale Gesundheitsindustrie unglaublich zu beeinflussen, indem sie …
das Potenzial, die globale Gesundheitsindustrie unglaublich zu beeinflussen, indem sie …
Substituent effect parameters: extending the applications to organometallic chemistry
Typically, metal complexes are constituted of an acceptor metal ion and one or more Iigands
containing the donor atoms. Accordingly, the properties of a metal complex are equally …
containing the donor atoms. Accordingly, the properties of a metal complex are equally …