Evolution of cyclic di-GMP signalling on a short and long term time scale

U Römling, LY Cao, FW Bai - Microbiology, 2023 - microbiologyresearch.org
Diversifying radiation of domain families within specific lineages of life indicates the
importance of their functionality for the organisms. The foundation for the diversifying …

Structural and functional diversity of bacterial cyclic nucleotide perception by CRP proteins

E Krol, L Werel, LO Essen, A Becker - Microlife, 2023 - academic.oup.com
Cyclic AMP (cAMP) is a ubiquitous second messenger synthesized by most living
organisms. In bacteria, it plays highly diverse roles in metabolism, host colonization, motility …

What's the matter with MICs: Bacterial nutrition, limiting resources, and antibiotic pharmacodynamics

BA Berryhill, T Gil-Gil, JA Manuel, AP Smith… - Microbiology …, 2023 - Am Soc Microbiol
The MIC of an antibiotic required to prevent replication is used both as a measure of the
susceptibility/resistance of bacteria to that drug and as the single pharmacodynamic …

Bacteria employ lysine acetylation of transcriptional regulators to adapt gene expression to cellular metabolism

M Kremer, S Schulze, N Eisenbruch, F Nagel… - Nature …, 2024 - nature.com
Abstract The Escherichia coli TetR-related transcriptional regulator RutR is involved in the
coordination of pyrimidine and purine metabolism. Here we report that lysine acetylation …

How bacterial pathogens coordinate appetite with virulence

ND Pokorzynski, EA Groisman - Microbiology and Molecular …, 2023 - Am Soc Microbiol
Cells adjust growth and metabolism to nutrient availability. Having access to a variety of
carbon sources during infection of their animal hosts, facultative intracellular pathogens …

Stenotrophomonas maltophilia virulence: a current view

V Mikhailovich, R Heydarov, D Zimenkov… - Frontiers in …, 2024 - frontiersin.org
Stenotrophomonas maltophilia is an opportunistic pathogen intrinsically resistant to multiple
and broad-spectrum antibiotics. Although the bacterium is considered a low-virulence …

Spatiotemporal coupling of DNA supercoiling and genomic sequence organization—a timing chain for the bacterial growth cycle?

G Muskhelishvili, P Sobetzko, A Travers - Biomolecules, 2022 - mdpi.com
In this article we describe the bacterial growth cycle as a closed, self-reproducing, or
autopoietic circuit, reestablishing the physiological state of stationary cells initially inoculated …

Heterologous Expression of Phycocyanobilin in Escherichia coli and Determination of Its Antioxidant Capacity In Vitro

Z Ye, J Fang, B Yao, G Liu - Molecular Biotechnology, 2024 - Springer
Phycocyanobilin (PCB) is a blue pigment with antioxidant, anti-inflammatory, and anticancer
properties. It is used in the medical and cosmetic industries. In this study, a high-expression …

[HTML][HTML] The regulatory effects of (p) ppGpp and indole on cAMP synthesis in Escherichia coli cells

NM Kashevarova, EA Khaova… - Vavilov Journal of …, 2024 - ncbi.nlm.nih.gov
Bacterial stress adaptive response is formed due to changes in the cell gene expression
profile in response to alterations in environmental conditions through the functioning of …

Регуляторные эффекты (p) ppGpp и индола на синтез цАМФ в клетках Escherichia coli

НМ Кашеварова, ЕА Хаова… - … журнал генетики и …, 2024 - vavilov.elpub.ru
Аннотация Адаптивный ответ бактерий на стрессорное воздействие условий среды
формируется за счет изменения генно-экспрессионного профиля клетки посредством …