The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy
Endothelial cells are at the interface between circulating blood and tissues. This position
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …
Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …
Heparan sulfate biosynthesis and sulfation profiles as modulators of cancer signalling and progression
Heparan Sulfate Proteoglycans (HSPGs) are important cell surface and Extracellular Matrix
(ECM) maestros involved in the orchestration of multiple cellular events in physiology and …
(ECM) maestros involved in the orchestration of multiple cellular events in physiology and …
Epitranscriptome analysis of oxidative stressed retinal epithelial cells depicted a possible RNA editing landscape of retinal degeneration
L Donato, C Scimone, S Alibrandi, SZ Scalinci… - Antioxidants, 2022 - mdpi.com
Oxidative stress represents one of the principal causes of inherited retinal dystrophies, with
many related molecular mechanisms still unknown. We investigated the posttranscriptional …
many related molecular mechanisms still unknown. We investigated the posttranscriptional …
Binding of the SARS-CoV-2 spike protein to glycans
W Hao, B Ma, Z Li, X Wang, X Gao, Y Li, B Qin… - Science Bulletin, 2021 - Elsevier
The pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a high number of deaths in the world. To combat it, it is necessary to develop a better …
caused a high number of deaths in the world. To combat it, it is necessary to develop a better …
Effect of microgravity on endothelial cell function, angiogenesis, and vessel remodeling during wound healing
L Morbidelli, S Genah, F Cialdai - Frontiers in bioengineering and …, 2021 - frontiersin.org
Wound healing is a complex phenomenon that involves different cell types with various
functions, ie, keratinocytes, fibroblasts, and endothelial cells, all influenced by the action of …
functions, ie, keratinocytes, fibroblasts, and endothelial cells, all influenced by the action of …
Spatiotemporal diversity and regulation of glycosaminoglycans in cell homeostasis and human disease
Glycosaminoglycans (GAGs) are long, linear polysaccharides that are ubiquitously
expressed on the cell surface and in the extracellular matrix of all animal cells. These …
expressed on the cell surface and in the extracellular matrix of all animal cells. These …
Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function
H Maldonado, BD Savage, HR Barker, U May… - Nature …, 2023 - nature.com
CAR (CARSKNKDC) is a wound-homing peptide that recognises angiogenic neovessels.
Here we discover that systemically administered CAR peptide has inherent ability to …
Here we discover that systemically administered CAR peptide has inherent ability to …
Syndecan receptors: pericellular regulators in development and inflammatory disease
The syndecans are the major family of transmembrane proteoglycans, usually bearing
multiple heparan sulfate chains. They are present on virtually all nucleated cells of …
multiple heparan sulfate chains. They are present on virtually all nucleated cells of …
Polysaccharides catabolism by the human gut bacterium -Bacteroides thetaiotaomicron: advances and perspectives
M Ye, J Yu, X Shi, J Zhu, X Gao… - Critical reviews in food …, 2021 - Taylor & Francis
In recent years, the degradation processes of polysaccharides by human gut microbiota are
receiving considerable attention due to the discoveries of the powerful function of gut …
receiving considerable attention due to the discoveries of the powerful function of gut …