Advances in the roles and mechanisms of lignans against Alzheimer's disease

N Han, Y Wen, Z Liu, J Zhai, S Li, J Yin - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Alzheimer's disease (AD) is a serious neurodegenerative disease associated
with the memory and cognitive impairment. The occurrence of AD is due to the accumulation …

Effects of intermittent fasting on cognitive health and Alzheimer's disease

A Elias, N Padinjakara, NT Lautenschlager - Nutrition reviews, 2023 - academic.oup.com
Objective Caloric restriction by intermittent fasting produces several metabolic changes,
such as increased insulin sensitivity and use of ketone bodies as energy sources. In …

Lipid levels and the risk of dementia: A dose–response meta‐analysis of prospective cohort studies

Y Zhu, X Liu, R Zhu, J Zhao… - Annals of Clinical and …, 2022 - Wiley Online Library
Objectives We performed a dose–response meta‐analysis to estimate the association
between lipid profiles with the risk of dementia and the potential differences according to the …

Ischemia as a common trigger for Alzheimer's disease

K Elman-Shina, S Efrati - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Alzheimer's disease has various potential etiologies, all culminating in the accumulation of
beta-amyloid derivatives and significant cognitive decline. Vascular-related pathology is one …

Multifocal cerebral microinfarcts modulate early Alzheimer's disease pathology in a sex-dependent manner

S Lecordier, V Pons, S Rivest, A ElAli - Frontiers in Immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) constitutes a major cause of dementia, affecting more women than
men. It is characterized by amyloid-β (Aβ) deposition and neurofibrillary tangles (NFTs) …

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

FS Hackenhaar, M Josefsson, AN Adolfsson… - Alzheimer's research & …, 2021 - Springer
Background Leukocyte telomere length (LTL) has been shown to predict Alzheimer's
disease (AD), albeit inconsistently. Failing to account for the competing risks between AD …

Genetic predisposition to low-density lipoprotein cholesterol may increase risks of both individual and familial Alzheimer's disease

JS Tan, MJ Hu, YM Yang, YJ Yang - Frontiers in Medicine, 2022 - frontiersin.org
Background: Previous observational studies provided conflicting results on the association
between low-density lipoprotein cholesterol (LDL-C) level and the risk of Alzheimer's …

Normal-tension glaucoma and potential clinical links to Alzheimer's disease

K Ho, NE Bodi, TP Sharma - Journal of Clinical Medicine, 2024 - mdpi.com
Glaucoma is a group of optic neuropathies and the world's leading cause of irreversible
blindness. Normal-tension glaucoma (NTG) is a subtype of glaucoma that is characterized …

High-density lipoprotein in Alzheimer's disease: From potential biomarkers to therapeutics

Y **, K Chifodya, G Han, W Jiang, Y Chen… - Journal of Controlled …, 2021 - Elsevier
The inverse correlation between high-density lipoprotein (HDL) levels in vivo and the risk of
Alzheimer's disease (AD) has become an inspiration for HDL-inspired AD therapy, including …

Cell-Type-Specific Neuroproteomics of Synapses

YY Yim, EJ Nestler - Biomolecules, 2023 - mdpi.com
In the last two decades, our knowledge of synaptic proteomes and their relationship to
normal brain function and neuropsychiatric disorders has been expanding rapidly through …