Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Intermediate filaments (IFs) play a key role in the integration of structure and function of
striated muscle, primarily by mediating mechanochemical links between the contractile …

Nuclear movement and positioning within cells has become an area of great interest in the
past few years due to the identification of different molecular mechanisms and functions in …

The most recent information on fascial tissue indicates that there are not fascial layers, but
polyhedral microvacuoles of connective tissue, which connect the body systems and, by …

Skeletal muscle is composed of multinucleated, mature muscle cells (myofibers) responsible
for contraction, and a resident pool of mononucleated muscle cell precursors (MCPs), that …

Background Dilated cardiomyopathy (DCM) could be caused by mutations in more than 40
different genes. However, the pathogenic impact of specific mutations is in most cases …

Membraneless organelles have emerged during the evolution of eukaryotic cells as
intracellular domains in which multiple proteins organize into complex structures to perform …

The mechanisms involved in the development of skeletal muscle fibers have been studied in
the last 70 years and yet many aspects of this process are still not completely understood. A …

The cholesterol synthesis inhibitor simvastatin, which is used to treat cardiovascular
diseases, has severe collateral effects. We decided to comprehensively study the effects of …

We examined ultrastructure protective phenomena and mechanisms of slow and fast
muscles in hibernating Daurian ground squirrels (Spermophilus dauricus). Some …