[HTML][HTML] The gut–organ-axis concept: Advances the application of gut-on-chip technology
The intestine is considered to be a vital digestive organ to absorb nutrients and is the largest
immune organ, while numerous microorganisms coexist with the host. It is well known that …
immune organ, while numerous microorganisms coexist with the host. It is well known that …
Gut-on-a-chip for disease models
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organ-on-a-chip-devices as robust in vitro models aiming to recapitulate organ 3D …
organ-on-a-chip-devices as robust in vitro models aiming to recapitulate organ 3D …
Impact of contaminants on microbiota: linking the gut–brain axis with neurotoxicity
J Balaguer-Trias, D Deepika, M Schuhmacher… - International Journal of …, 2022 - mdpi.com
Over the last years, research has focused on microbiota to establish a missing link between
neuronal health and intestine imbalance. Many studies have considered microbiota as …
neuronal health and intestine imbalance. Many studies have considered microbiota as …
Archaea from the gut microbiota of humans: Could be linked to chronic diseases?
D Mafra, M Ribeiro, L Fonseca, B Regis… - Anaerobe, 2022 - Elsevier
Archaea comprise a unique domain of organisms with distinct biochemical and genetic
differences from bacteria. Methane-forming archaea, methanogens, constitute the …
differences from bacteria. Methane-forming archaea, methanogens, constitute the …
[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery
T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
Quorum sensing in human gut and food microbiomes: Significance and potential for therapeutic targeting
AK Falà, A Álvarez-Ordóñez, A Filloux… - Frontiers in …, 2022 - frontiersin.org
Human gut and food microbiomes interact during digestion. The outcome of these
interactions influences the taxonomical composition and functional capacity of the resident …
interactions influences the taxonomical composition and functional capacity of the resident …
Gut microbial metabolic signatures in diabetes mellitus and potential preventive and therapeutic applications
E Garcia-Gutierrez, AK O'Mahony, RS Dos Santos… - Gut …, 2024 - Taylor & Francis
Diabetes mellitus can be subdivided into several categories based on origin and clinical
characteristics. The most common forms of diabetes are type 1 (T1D), type 2 diabetes (T2D) …
characteristics. The most common forms of diabetes are type 1 (T1D), type 2 diabetes (T2D) …
Organ‐on‐a‐chip technologies for biomedical research and drug development: A focus on the vasculature
D Soto Veliz, KL Lin, C Sahlgren - Smart medicine, 2023 - Wiley Online Library
Current biomedical models fail to replicate the complexity of human biology. Consequently,
almost 90% of drug candidates fail during clinical trials after decades of research and …
almost 90% of drug candidates fail during clinical trials after decades of research and …