Iron overload is a systemic disorder and is either primary (genetic) or secondary (exogenous
iron administration). Primary iron overload is most commonly associated with hereditary …

The collagen network is altered in fibrotic diseases associated with extracellular matrix
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …

Molecular imaging holds the potential for noninvasive and accurate grading of liver fibrosis.
It is limited by the lack of biomarkers that strongly correlate with liver fibrosis grade. Here, we …

Liver MR elastography is an imaging technique used to measure liver stiffness in the
evaluation for possible fibrosis or cirrhosis. Liver stiffness measurement (LSM) is useful for …

From the development of x-ray imaging in the late 19th century, the field of medical imaging
developed an impressive array of modalities. These can measure and image a variety of …

Fibrosis plays an important role in many different pathologies. It results from tissue injury,
chronic inflammation, autoimmune reactions and genetic alterations, and it is characterized …

Over the past two decades, the epidemiology of chronic liver disease has changed with an
increase in the prevalence of nonalcoholic fatty liver disease in parallel to the advent of …

Liver fibrosis is an important pathological precondition for hepatocellular carcinoma. The
degree of hepatic fibrosis is positively correlated with liver cancer. Liver fibrosis is a series of …

A critical step in quasi-static ultrasound elastography is the estimation of time delay between
two frames of radio-frequency (RF) data that are obtained while the tissue is undergoing …

Objective To develop a quantitative ultrasound (QUS)-and elastography-based model to
improve classification of steatosis grade, inflammation grade, and fibrosis stage in patients …