Pharmaceutical properties of macrocyclic Schiff base transition metal complexes: urgent need in today's world

M Yadav, D Yadav, DP Singh, JK Kapoor - Inorganica Chimica Acta, 2023 - Elsevier
The World is facing an epidemic of various diseases caused by viruses, bacteria, and fungi.
Apart from it, cancer, malaria, and diabetes are some major health problems. So, a need …

Synthesis, antimicrobial evaluation, molecular docking and theoretical calculations of novel pyrazolo [1, 5-a] pyrimidine derivatives

AM Fahim, AM Farag - Journal of Molecular Structure, 2020 - Elsevier
New fused heterocyclic compounds were synthesized starting from dimethyl terephthalate,
as a versatile precursor, via its reactions with the appropriate reagents. The structures of the …

Recent advances of Schiff base metal complexes as potential anticancer agents

L Lv, T Zheng, L Tang, Z Wang, W Liu - Coordination Chemistry Reviews, 2025 - Elsevier
The successful clinical application of Pt-based drugs in anticancer therapy has stimulated
interest in the development of metallodrugs. Numerous metal complexes with significant …

Ni (II), Co (II), Fe (III), and Zn (II) mixed ligand complexes of indoline-dione and naphthalene-dione: Synthesis, characterization, thermal, antimicrobial, and molecular …

EM Zayed, GG Mohamed, HA Abd El Salam - Inorganic Chemistry …, 2023 - Elsevier
New mixed ligand complexes with metal ions (Ni (II), Co (II), Zn (II), and Fe (III)) of the type
[ML 1 L 2](where L 1= indoline-2, 3-dione and L 2= naphthalene-1, 2-dione) were …

Synthesis, biological evaluation and DFT calculation of novel pyrazole and pyrimidine derivatives

AM Farag, AM Fahim - Journal of Molecular Structure, 2019 - Elsevier
The utility of the enaminonitriles 3a and 3b for the synthesis of the pyrazole derivatives 5a, b,
7a, b, diaminopyrimidine derivatives 9, 11, pyrazolo [1, 5-a] pyrimidines 12, 15, triazolo [4, 3 …

Synthesis, antimicrobial activity, theoretical investigation, and electrochemical studies of cellulosic metal complexes

AM Fahim, M Hasanin, IHI Habib, RO El-Attar… - Journal of the Iranian …, 2023 - Springer
In this explanation, we explained how to make 5-amino-1, 3, 4-thiadiazol cellulose by
reacting carboxymethyl cellulose (CMC) with thiosemicarbazide and undergoing …

Synthesis, antimicrobial and antiproliferative activities, molecular docking, and computational studies of novel heterocycles

AM Fahim, HEM Tolan, H Awad, EHI Ismael - Journal of the Iranian …, 2021 - Springer
We studied the reaction of enaminone 3 with some nitrogen nucleophiles to afford the
corresponding pyrazole 4, isoxazole 5, and pyrimidine 6 derivatives, and the reactivity of …

Experimental and theoretical studies of some propiolate esters derivatives

AM Fahim, A Mohamed, MA Ibrahim - Journal of Molecular Structure, 2021 - Elsevier
In this study, we synthesized some propiolate esters derivatives via Steglich
esterificationand investigated utilized experimental and theoretical calculations. The …

[HTML][HTML] Cytotoxic urea Schiff base complexes for multidrug discovery as anticancer activity and low in vivo oral assessing toxicity

LM Aroua, AN Al-Hakimi, MAM Abdulghani… - Arabian Journal of …, 2022 - Elsevier
Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …

Synthesis, biological evaluation, molecular docking and DFT calculations of novel benzenesulfonamide derivatives

AM Fahim, MA Shalaby - Journal of Molecular Structure, 2019 - Elsevier
Abstract The reaction of N-(4-acetylphenyl) benzene sulphonamide derivatives 3a and 3b
with N, N dimethyl formamide dimethyl acetal (DMF-DMA) afford acryloyl (phenyl) …