Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …

Glioblastoma (GBM), the most aggressive form of brain cancer, has witnessed very little
clinical progress over the last decades, in part, due to the absence of effective drug delivery …

Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …

Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …

Dendrimers are discrete nanostructures/nanoparticles with 'onion skin‐like'branched layers.
Beginning with a core, these nanostructures grow in concentric layers to produce stepwise …

Human neuroscience has made remarkable progress in understanding basic aspects of
functional organization; it is a renowned fact that the blood–brain barrier (BBB) impedes the …

Highlights•Dendrimers are nanovectors with well-defined architecture and tunable surface
characteristics.•Dendrimers can take advantage of passive and active tumor targeting for …

Drugs are introduced into the body by numerous routes such as enteral (oral, sublingual and
rectum administration), parenteral (intravascular, intramuscular, subcutaneous and …