Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

The review lays emphasis on the significance of 1, 2, 3-triazoles synthesized via CuAAC
reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory …

Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Methicillin-resistant Staphylococcus aureus (MRSA), as a classic reason for genuine skin
and flimsy tissues diseases, is a worldwide general wellbeing risk and has already …

Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

Infections caused by Gram‐positive and‐negative bacteria are one of the foremost causes of
morbidity and mortality globally. Antibiotics are the mainstay of therapy for bacterial …

Alzheimer's disease (AD) is a well known neurodegenerative disorder alarming millions of
people worldwide and the subsequent epidemiological statistics highlights the implication of …

A series of around eight novel chalcone based coumarin derivatives (23a-h) was designed,
subjected to in-silico ADMET prediction, synthesized, characterized by IR, NMR, Mass …

Coumarin hybrids have been designed and synthesized as an important new strategy in the
field of medicinal chemistry. Coumarin core has been shown to form various compounds to …

In this study, a series of bis–and tetrakis–1, 2, 3–triazole derivatives were synthesized using
copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry in 73–95% yield. The …