Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment

MA Malla, A Dubey, A Kumar, S Yadav… - Frontiers in …, 2019 - frontiersin.org
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

[PDF][PDF] Computational pan-genomics: status, promises and challenges

Briefings in bioinformatics, 2018 - academic.oup.com
Many disciplines, from human genetics and oncology to plant breeding, microbiology and
virology, commonly face the challenge of analyzing rapidly increasing numbers of genomes …

The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

M Jain, HE Olsen, B Paten, M Akeson - Genome biology, 2016 - Springer
Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

J Quick, ND Grubaugh, ST Pullan, IM Claro, AD Smith… - Nature protocols, 2017 - nature.com
Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and …

GenASM: A high-performance, low-power approximate string matching acceleration framework for genome sequence analysis

DS Cali, GS Kalsi, Z Bingöl, C Firtina… - 2020 53rd Annual …, 2020 - ieeexplore.ieee.org
Genome sequence analysis has enabled significant advancements in medical and scientific
areas such as personalized medicine, outbreak tracing, and the understanding of evolution …

[HTML][HTML] MinION Analysis and Reference Consortium: Phase 1 data release and analysis

CLC Ip, M Loose, JR Tyson, M de Cesare… - …, 2015 - ncbi.nlm.nih.gov
The advent of a miniaturized DNA sequencing device with a high-throughput contextual
sequencing capability embodies the next generation of large scale sequencing tools. The …

Recent progress in solid‐state nanopores

K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

A world of opportunities with nanopore sequencing

RM Leggett, MD Clark - Journal of experimental botany, 2017 - academic.oup.com
Abstract Oxford Nanopore Technologies' MinION sequencer was launched in pre-release
form in 2014 and represents an exciting new sequencing paradigm. The device offers multi …

An introduction to nanopore sequencing: past, present, and future considerations

M MacKenzie, C Argyropoulos - Micromachines, 2023 - mdpi.com
There has been significant progress made in the field of nanopore biosensor development
and sequencing applications, which address previous limitations that restricted widespread …

Metagenomic nanopore sequencing of influenza virus direct from clinical respiratory samples

K Lewandowski, Y Xu, ST Pullan… - Journal of clinical …, 2019 - Am Soc Microbiol
Influenza is a major global public health threat as a result of its highly pathogenic variants,
large zoonotic reservoir, and pandemic potential. Metagenomic viral sequencing offers the …