Syndromes of thrombotic microangiopathy
JN George, CM Nester - New England Journal of Medicine, 2014 - Mass Medical Soc
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Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic
microangiopathy characterized by microangiopathic hemolytic anemia, severe …
microangiopathy characterized by microangiopathic hemolytic anemia, severe …
In vitro microvessels for the study of angiogenesis and thrombosis
Microvascular networks support metabolic activity and define microenvironmental conditions
within tissues in health and pathology. Recapitulation of functional microvascular structures …
within tissues in health and pathology. Recapitulation of functional microvascular structures …
Pathophysiology of thrombotic thrombocytopenic purpura
JE Sadler - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif,
member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic …
member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic …
Endothelium—role in regulation of coagulation and inflammation
By its strategic position at the interface between blood and tissues, endothelial cells control
blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory …
blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory …
[HTML][HTML] von Willebrand factor and inflammation
C Kawecki, PJ Lenting, CV Denis - Journal of Thrombosis and Haemostasis, 2017 - Elsevier
Von Willebrand factor (VWF) is a plasma glycoprotein best known for its crucial hemostatic
role in serving as a molecular bridge linking platelets to subendothelial components …
role in serving as a molecular bridge linking platelets to subendothelial components …
The growing complexity of platelet aggregation
Platelet aggregation, the process by which platelets adhere to each other at sites of vascular
injury, has long been recognized as critical for hemostatic plug formation and thrombosis …
injury, has long been recognized as critical for hemostatic plug formation and thrombosis …
Thrombotic thrombocytopenic purpura
JN George - New England Journal of Medicine, 2006 - Mass Medical Soc
A 40-year-old obese black woman has had weakness and epigastric pain for several weeks
and diarrhea and vomiting for four days. She does not appear acutely ill; the physical …
and diarrhea and vomiting for four days. She does not appear acutely ill; the physical …
Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and …
Background Thrombotic thrombocytopenic purpura (TTP) associated with severe, acquired
ADAMTS13 deficiency is uncommonly reported in children. The incidence, demographic …
ADAMTS13 deficiency is uncommonly reported in children. The incidence, demographic …
The vessel wall and its interactions
Blood cell interactions with the vessel wall were first documented almost 170 years ago.
Modern advances have revealed that leukocyte and platelet interactions with the …
Modern advances have revealed that leukocyte and platelet interactions with the …