In the central nervous system (CNS), connexin (Cx) s and pannexin (Panx) s are an integral
component of homeostatic neuronal excitability and synaptic plasticity. Neuronal Cx gap …

Gap junction (GJ) channels and their connexins (Cxs) are complex proteins that have
essential functions in cell communication processes in the central nervous system (CNS) …

Adult neurogenesis is a striking example of neuroplasticity, which enables adaptive network
remodelling in response to all forms of environmental stimulation in physiological and …

The incidence of brain pathologies has increased during last decades. Better diagnosis
(autism spectrum disorders) and longer life expectancy (Parkinson's disease, Alzheimer's …

Abnormalities of alpha-synuclein (ASN), the main component of protein deposits (Lewy
bodies), were observed in Parkinson's disease (PD), dementia with Lewy bodies …

During the development of the vertebrate nervous systems, genetic programs assemble an
immature circuit that is subsequently refined by neuronal activity evoked by external stimuli …

In the mammalian brain, cortical interneurons (INs) are a highly diverse group of cells. A key
neurophysiological question concerns how each class of INs contributes to cortical circuit …

The DNA-binding protein SATB2 is genetically linked to human intelligence. We studied its
influence on the three-dimensional (3D) epigenome by map** chromatin interactions and …

Purinergic signaling encompasses the cycle of adenosine 5′ triphosphate (ATP) release
and its metabolism into nucleotide and nucleoside derivatives, the direct release of …

Pannexin1 (Panx1) is expressed in both neurons and glia where it forms ATP-permeable
channels that are activated under pathological conditions such as epilepsy, migraine …