Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Recognition and treatment of cognitive dysfunction in major depressive disorder

H Zuckerman, Z Pan, C Park, E Brietzke… - Frontiers in …, 2018 - frontiersin.org
Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …

The clinical characterization of the adult patient with depression aimed at personalization of management

M Maj, DJ Stein, G Parker, M Zimmerman… - World …, 2020 - Wiley Online Library
Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 1 …

RW Lam, D McIntosh, JL Wang… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Cognitive impairment in major depressive disorder

Z Pan, C Park, E Brietzke, H Zuckerman, C Rong… - CNS …, 2019 - cambridge.org
Cognitive dysfunction is a symptomatic domain identified across many mental disorders.
Cognitive deficits in individuals with major depressive disorder (MDD) contribute …

Map** risk factors for depression across the lifespan: an umbrella review of evidence from meta-analyses and Mendelian randomization studies

CA Köhler, E Evangelou, B Stubbs, M Solmi… - Journal of psychiatric …, 2018 - Elsevier
The development of depression may involve a complex interplay of environmental and
genetic risk factors. PubMed and PsycInfo databases were searched from inception through …

The effects of vortioxetine on cognitive function in patients with major depressive disorder: a meta-analysis of three randomized controlled trials

RS McIntyre, J Harrison, H Loft… - International Journal …, 2016 - academic.oup.com
Background: Management of cognitive deficits in Major Depressive Disorder (MDD) remains
an important unmet need. This meta-analysis evaluated the effects of vortioxetine on …

The clinical relationship between cognitive impairment and psychosocial functioning in major depressive disorder: A systematic review

OR Cambridge, MJ Knight, N Mills, BT Baune - Psychiatry research, 2018 - Elsevier
Cognitive deficits are frequently observed in major depressive disorder (MDD), as well as
impaired long-term psychosocial functioning. However, the relationship between cognitive …

[HTML][HTML] Effects of physical exercise on executive function in adults with depression: a systematic review and meta-analysis

F Contreras-Osorio, R Ramirez-Campillo… - International journal of …, 2022 - mdpi.com
Executive function is among the most affected cognitive dimensions in depression. Physical
exercise may improve executive function (eg, working memory, inhibition, cognitive …

Cannabidiol in medical marijuana: research vistas and potential opportunities

C Rong, Y Lee, NE Carmona, DS Cha… - Pharmacological …, 2017 - Elsevier
The high and increasing prevalence of medical marijuana consumption in the general
population invites the need for quality evidence regarding its safety and efficacy. Herein, we …