Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition

R Menon, EA Bonney, J Condon… - Human reproduction …, 2016 - academic.oup.com
The signals and mechanisms that synchronize the timing of human parturition remain a
mystery and a better understanding of these processes is essential to avert adverse …

The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth

E Prairie, F Cote, M Tsakpinoglou, M Mina… - Cytokine & growth factor …, 2021 - Elsevier
Preterm birth (PTB) and its consequences are a major public health concern as preterm
delivery is the main cause of mortality and morbidity at birth. There are many causes of PTB …

Myometrial cytokines and their role in the onset of labour

SP Sivarajasingam, N Imami… - Journal of …, 2016 - joe.bioscientifica.com
Human labour is an inflammatory event, physiologically driven by an interaction between
hormonal and mechanical factors and pathologically associated with infection, bleeding and …

In pregnancy increased maternal STAI trait stress score shows decreased insulin sensitivity and increased stress hormones

G Valsamakis, DC Papatheodorou, N Chalarakis… - …, 2017 - Elsevier
Introduction Chronic or acute stressors influence maternal and fetal Hypothalamus-Pituitary-
Adrenal Axes (HPA) during pregnancy. In this study, the effect of maternal stress into …

Prenatal two-hit stress affects maternal and offspring pregnancy outcomes and uterine gene expression in rats: match or mismatch?

BSE Verstraeten, JK McCreary, S Weyers… - Biology of …, 2019 - academic.oup.com
Maternal stress and inflammation excesses can lead to adverse pregnancy outcomes and
offspring development. We evaluated whether distinct prenatal stressors affect pregnancy …

[HTML][HTML] Corticotropin releasing hormone and the immune/inflammatory response

M Nezi, G Mastorakos, Z Mouslech - 2015 - europepmc.org
The immune/inflammatory (I/I) response is a reaction of the vascularized connective tissue,
characterized by the accumulation of fluid and leukocytes in extravascular tissues. In this …

Differences in inflammatory markers between nulliparous women admitted to hospitals in preactive vs active labor

JL Neal, JM Lamp, NK Lowe, SL Gillespie… - American journal of …, 2015 - Elsevier
Objective To determine whether labor-associated inflammatory markers differ between low-
risk, nulliparous women in preactive vs active labor at hospital admission and over time …

Cervical cerclage placement decreases local levels of proinflammatory cytokines in patients with cervical insufficiency

SP Monsanto, S Daher, E Ono, KPT Pendeloski… - American Journal of …, 2017 - Elsevier
Background Cervical insufficiency is characterized by premature, progressive dilation and
shortening of the cervix during pregnancy. If left unattended, this can lead to the prolapse …

A peripheral immune signature of labor induction

K Ando, JJ Hédou, D Feyaerts, X Han… - Frontiers in …, 2021 - frontiersin.org
Approximately 1 in 4 pregnant women in the United States undergo labor induction. The
onset and establishment of labor, particularly induced labor, is a complex and dynamic …

Increased prevalence of negative pregnancy and fetal outcomes in women with primary adrenal insufficiency. A systematic review and meta-analysis

G Ilia, G Paltoglou, C Chatzakis, P Christopoulos… - Endocrine, 2024 - Springer
Maternal primary adrenal insufficiency (PAI) during pregnancy, due to either Addison
disease (AD) or congenital adrenal hyperplasia (CAH), is rare. Only few studies have …