Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

In the course of examining the effect of electric fields on the growth of Escherichia coli cells,
a biological activity of platinum compounds was uncovered that led to the development of …

Abstract 'Pioneer'transcription factors are required for stem-cell pluripotency, cell
differentiation and cell reprogramming,. Pioneer factors can bind nucleosomal DNA to …

Principles of Nucleic Acid Structure, Second Edition, provides the most complete and
concise summary of underlying principles and approaches to studying nucleic acid structure …

Understanding the function of biological macromolecules and their complexes at the
physicochemical level requires knowledge of both their structure and dynamics …

In many eukaryotes, genetic sex determination is not governed by XX/XY or ZW/ZZ systems
but by a specialized region on the poorly studied U (female) or V (male) sex chromosomes …

Most extracellular proteins are secreted via the classical endoplasmic reticulum (ER)/Golgi-
dependent secretion pathway; however, some proteins, including a few danger-associated …

The nuclear Overhauser effect (NOE) is defined as the change in intensity of one NMR
resonance that occurs when another is saturated. It results from dipole–dipole cross …

THE success of cisplatin in cancer chemotherapy derives from its ability to crosslink DNA
and alter the structure. Most cisplatiná¤-DNA adducts are intrastrand d (GpG) and d (ApG) …

Integration host factor (IHF) is a small heterodimeric protein that specifically binds to DNA
and functions as an architectural factor in many cellular processes in prokaryotes. Here, we …