Brain aging is a complex process involving many functions of our body and described by the
interplay of a sleep pattern and changes in the metabolic waste concentration regulated by …

The SARS-CoV-2 pandemic urgently calls for the development of effective preventive tools.
COVID-19 hits greatly the elder and more fragile fraction of the population boosting the …

We propose a novel biologically plausible computational model of working memory (WM)
implemented by a spiking neuron network (SNN) interacting with a network of astrocytes …

Recent in vitro and in vivo experiments demonstrate that astrocytes participate in the
maintenance of cortical gamma oscillations and recognition memory. However, the …

Background Large observational clinical datasets are becoming increasingly available for
mining associations between various disease traits and administered therapy. These …

Mammalian brains operate in very special surroundings: to survive they have to react quickly
and effectively to the pool of stimuli patterns previously recognized as danger. Many …

Estimators of biological age (BA)–defined as the hypothetical underlying age of an organism–
have attracted more and more attention in the last years, especially after the advent of new …

Advanced age is the major risk factor for idiopathic Parkinson's disease (PD), but to date the
biological relationship between PD and ageing remains elusive. Here we describe the …

Living systems are subject to the arrow of time; from birth, they undergo complex
transformations (self-organization) in a constant battle for survival, but inevitably ageing and …

In this work, we consider a mathematical model describing spontaneous calcium signaling
in astrocytes. Based on biologically relevant principles, this model simulates experimentally …