Comparative oncology is a field of study that has been recently adopted for studying cancer
and develo** cancer therapies. Companion animals such as dogs can be used to …

Simple Summary Mammary tumors are the most frequent neoplasia in female dogs. They
develop spontaneous cancer and share several biological, clinical, pathological and …

Spontaneous canine cancers are valuable but relatively understudied and underutilized
models. To enhance their usage, we reanalyze whole exome and genome sequencing data …

Naturally occurring canine cancers have remarkable similarities to their human counterparts.
To better understand these similarities, we investigated 671 client-owned dogs from 96 …

Simple Summary The high rate of cancers in both humans and in animals along with their
poor overall survival pose a major challenge in medicine. Therefore, a large amount of …

Mammary tumors in dogs hold great potential as naturally occurring breast cancer models in
translational oncology, as they share the same environmental risk factors, key histological …

Canine osteosarcoma is increasingly recognized as an informative model for human
osteosarcoma. Here we show in one of the largest clinically annotated canine osteosarcoma …

Simple Summary Genetic molecular testing is starting to become part of standard clinical
practice for dogs with cancer as it can assist veterinarians with diagnosis, provide …

Metastases originate from primary tumors and reach distant organs. Growing evidence
suggests that metastases are under the control of primary tumors even outside the primary …

Despite all clinical progress recorded in the last decades, human breast cancer (HBC)
remains a major challenge worldwide both in terms of its incidence and its management …