An overview of microRNAs
SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …
miRNA targets: from prediction tools to experimental validation
G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
Small RNAs in plants: recent development and application for crop improvement
The phenomenon of RNA interference (RNAi) which involves sequence-specific gene
regulation by small non-coding RNAs, ie, small interfering RNA (siRNA) and microRNA …
regulation by small non-coding RNAs, ie, small interfering RNA (siRNA) and microRNA …
Advances and challenges in the detection of transcriptome‐wide protein–RNA interactions
EC Wheeler, EL Van Nostrand… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
RNA binding proteins (RBPs) play key roles in determining cellular behavior by
manipulating the processing of target RNAs. Robust methods are required to detect the …
manipulating the processing of target RNAs. Robust methods are required to detect the …
Widespread RNA binding by chromatin-associated proteins
Background Recent evidence suggests that RNA interaction can regulate the activity and
localization of chromatin-associated proteins. However, it is unknown if these observations …
localization of chromatin-associated proteins. However, it is unknown if these observations …
RNA interference: concept to reality in crop improvement
The phenomenon of RNA interference (RNAi) is involved in sequence-specific gene
regulation driven by the introduction of dsRNA resulting in inhibition of translation or …
regulation driven by the introduction of dsRNA resulting in inhibition of translation or …
Bacterial argonaute samples the transcriptome to identify foreign DNA
Summary Eukaryotic Argonautes bind small RNAs and use them as guides to find
complementary RNA targets and induce gene silencing. Though homologs of eukaryotic …
complementary RNA targets and induce gene silencing. Though homologs of eukaryotic …
[HTML][HTML] MicroRNA target recognition: insights from transcriptome-wide non-canonical interactions
H Seok, J Ham, ES Jang, SW Chi - Molecules and cells, 2016 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs (∼ 22 nucleotides) regulating gene
expression at the post-transcriptional level. By directing the RNA-induced silencing complex …
expression at the post-transcriptional level. By directing the RNA-induced silencing complex …
CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53
R Saldaña-Meyer, E González-Buendía… - Genes & …, 2014 - genesdev.cshlp.org
The multifunctional CCCTC-binding factor (CTCF) protein exhibits a broad range of
functions, including that of insulator and higher-order chromatin organizer. We found that …
functions, including that of insulator and higher-order chromatin organizer. We found that …
Antiviral RNAi in insects and mammals: parallels and differences
The RNA interference (RNAi) pathway is a potent antiviral defense mechanism in plants and
invertebrates, in response to which viruses evolved suppressors of RNAi. In mammals, the …
invertebrates, in response to which viruses evolved suppressors of RNAi. In mammals, the …