[HTML][HTML] Gastroretentive technologies in tandem with controlled-release strategies: A potent answer to oral drug bioavailability and patient compliance implications

NN Vrettos, CJ Roberts, Z Zhu - Pharmaceutics, 2021‏ - mdpi.com
There have been many efforts to improve oral drug bioavailability and therapeutic efficacy
and patient compliance. A variety of controlled-release oral delivery systems have been …

Polymeric excipients in the technology of floating drug delivery systems

EV Blynskaya, SV Tishkov, VP Vinogradov… - Pharmaceutics, 2022‏ - mdpi.com
The combination of targeted transport and improvement of the release profile of the active
pharmaceutical ingredient (API) is a current trend in the development of oral medicinal …

Release kinetics of highly porous floating tablets containing cilostazol

KM Hwang, CH Cho, NT Tung, JY Kim, YS Rhee… - European Journal of …, 2017‏ - Elsevier
This study focuses on develo** a highly porous floating tablet containing cilostazol. The
underlying release mechanism of cilostazol from porous and floating tablets in dissolution …

Swellable and porous bilayer tablet for gastroretentive drug delivery: Preparation and in vitro-in vivo evaluation

KM Hwang, TT Nguyen, SH Seok, HI Jo, CH Cho… - International Journal of …, 2019‏ - Elsevier
The purpose of this study was to develop a novel gastroretentive drug delivery system with
immediate buoyancy and high wet strength. The proposed bilayer tablet was composed of a …

Determination and correlation of solubility of sarpogrelate hydrochloride in eight solvents at different temperatures

ES Ha, DH Kuk, DH Ha, WY Sim, I Baek, JS Kim… - Journal of Molecular …, 2017‏ - Elsevier
In this study, the solubility of sarpogrelate hydrochloride in methanol, ethanol, 1-propanol, 2-
propanol, 1-butanol, acetone, acetonitrile, and tetrahydrofuran was determined at …

Modern Approaches to Obtaining Floating Drug Dosage Forms (A Review)

EV Blynskaya, VP Vinogradov, SV Tishkov… - Pharmaceutical …, 2022‏ - Springer
Floating dosage forms (FDFs) represent widely used types of gastroretentive drug delivery
systems that provide targeted delivery to the upper gastrointestinal tract. This article …

Controlled release of MT-1207 using a novel gastroretentive bilayer system comprised of hydrophilic and hydrophobic polymers

NN Vrettos, P Wang, Y Wang, CJ Roberts… - Pharmaceutical …, 2023‏ - Taylor & Francis
In the present study, novel gastroretentive bilayer tablets were developed that are promising
for the once-a-day oral delivery of the drug candidate MT-1207. The gastroretentive layer …

Современные подходы в области получения флотирующих лекарственных форм (обзор)

ЕВ Блынская, ВП Виноградов, СВ Тишков… - Химико …, 2022‏ - chem.folium.ru
Аннотация Плавающие, или флотирующие лекарственные формы (ФЛФ)
представляют собой разновидность гастроретентивных систем доставки …

Medicated Supportive Braces: A Synergy of Treatments for Joint Pain Relief

D Limbasiya, D Mehta - Drug Delivery Letters, 2022‏ - benthamdirect.com
Background and Objectives: The present study unveils a simple but innovative combination
of existing treatments of three different domains with unique logical aspects. Joint pain is the …